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This study found that PNU 157706 is a highly potent inhibitor of human 5α-reductase enzymes, showing a stronger and longer-lasting antiprostatic effect in rats compared to finasteride.

This study found that Golvatinib, Gliquidone, and Dihydroergotamine may inhibit the binding of SARS-CoV-2's Nsp1 protein to the host ribosomal subunit, suggesting potential as treatments against COVID-19 variants.

This study found that cholesterol- and phospholipid-free multilamellar niosomes improved skin deposition and targeted deeper hair follicles better than hydrophobic PLGA nanoparticles for transdermal drug delivery.

This study reviewed recent scientific evidence on the neuroendocrine and metabolic impacts of chronic use of 5-alpha reductase inhibitors, detailing its association with sexual dysfunction, mood disorders, insulin resistance, and other metabolic disorders, suggesting persistent biopsycho-social risks beyond transient side effects in users.

This study found that Spironolactone-loaded ethosomal gels provided superior skin permeation and deposition compared to niosomal gels in rabbit skin, suggesting that ethosomal gels could be a promising formulation for further clinical studies on treating androgenic alopecia.

This study evaluated a new nanogel formulation containing Ciclopirox Olamine for treating cutaneous candidiasis, finding that the optimized version offered improved skin penetration, sustained drug release, and effective antifungal action against Candida albicans compared to conventional treatment.

This study found that topical niosomal minoxidil significantly increased hair count and patient satisfaction compared to conventional minoxidil in men with androgenetic alopecia.

This study developed cilostazol-loaded formulations for nose-to-brain delivery, finding that these formulations improved cilostazol's bioavailability by enhancing solubility, absorption, and permeability, achieving nearly 100% drug release in vitro within 2 hours.

This study found that finasteride delivered through a nano-transferosomal gel showed improved penetration through skin layers compared to a conventional gel, suggesting a potential alternative for oral administration.

This study formulated and characterized a dutasteride-loaded nanocrystalline suspension for long-acting parenteral delivery, finding that it provided sustained drug release in rats with a significant reduction in local inflammation over 28 days following intramuscular injection.

Hydrogel microneedles with special nanoparticles and growth factor improve hair growth better than minoxidil for hair loss treatment.

This study found that SER120 nasal spray significantly improved nocturia symptoms and quality of life compared to placebo in patients 50 years and older, with both tested doses showing efficacy and an acceptable safety profile over a 12-week period.

This study reported that the new near-infrared LED device showed significant improvements in skin rejuvenation and a slight increase in hair growth, with further research recommended for broader validation.

This paper presents a new device for navigational surgery utilizing the fluorescent properties of Indocyanine Green, offering enhanced intra-operative imaging capabilities by identifying tissues with an infrared CMOS camera.

Isoginkgetin reduces inflammation in cells by blocking NF-κB activation.

Niosomal minoxidil, when applied topically, increases hair count more than conventional minoxidil solution.

NB-002 is a promising new topical treatment for fungal nail infections, showing better results than a non-medicated option.

In this study, applying FGF-2-containing dalteparin/protamine nanoparticles to the scalp was associated with a significant increase in hair diameter over six months among participants with thin hair.

This research discusses advancements in niosomal drug delivery systems, highlighting their promising potential to improve targeted drug delivery due to their ability to encapsulate various drug types efficiently, offering advantages over traditional liposome systems in terms of chemical stability and therapeutic efficacy.

This study reports that hedgehog pathway inhibitors, sonidegib and vismodegib, showed distinct adverse event patterns in real-world data, suggesting the need for further research to confirm these findings.

In this study, topical nitroglycerine spray successfully prevented impending necrosis in 94% of hair transplant cases showing signs of vascular distress.

This study found that treating mice with naringenin, alone or combined with minoxidil, significantly increased hair growth and follicle diameter and quantity, likely due to its antioxidant and anti-inflammatory properties.

This study found that neonatal administration of finasteride reduced sensitivity to alcohol's motor-stimulating effects and increased preference for novelty and initial alcohol consumption in rats, suggesting a role in alcohol vulnerability.

This review discusses how nanospanlastics, a type of ultra deformable vesicular nanocarrier, could enhance glaucoma management by improving the delivery and effectiveness of intraocular pressure-lowering agents, tackling adherence challenges, and advancing targeted therapies, according to the authors.

This report describes the successful use of sonidegib in treating two cases of locally advanced basal cell carcinoma, leading to remission in both instances, and reducing lesions in a patient with Gorlin syndrome, while noting mild side effects consistent with the drug's known profile.

Dutasteride is more effective than finasteride for hair growth, and pregabalin effectively treats neuropathic pain.

This study found that once-daily oxiconazole cream effectively treats tinea infections, achieving at least 80% cure rates, and shows comparable efficacy to other antifungal creams with similar tolerability.

This review highlights recent advancements in using niosomes as nanocarriers for improved delivery and sustained release of active cosmetic compounds, discussing their properties, applications, and future potential in cosmetic chemistry.