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Human skin can make serotonin and melatonin.

Targeted cancer therapies often cause serious skin problems that need careful management.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Estrogen therapy can reduce skin aging but has cancer risks.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Certain genes control the color of human hair by affecting pigment production.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Dermoscopy helps diagnose and monitor treatment for hair loss from scarring conditions like discoid lupus and lichen planopilaris.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Dermoscopy is useful for diagnosing various skin, hair, and nail disorders and can reduce the need for biopsies.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Taking too many vitamin and mineral supplements can cause serious health problems.

A boy with chromosome 13q deletion syndrome developed eye cancer, a woman with breast cancer lost vision due to a rare side-effect of her treatment, a man's vision worsened after using a hair loss drug, and two rare disorders were discussed. Optical Coherence Tomography is useful for diagnosing and monitoring these conditions.

Eye exams are crucial for kids with 13q deletion syndrome, tamoxifen can cause vision loss, Propecia may lead to cataracts, Lipoid Proteinosis causes skin bumps, and OCT is useful for diagnosing macular diseases.

Ruby laser hair removal significantly reduces hair density.

Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.

HGF/SF increases skin melanocytes but doesn't change melanin type or amount.

Trichoscopy helps quickly identify autoimmune diseases on the scalp but should be used with other standard tests.