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Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Cannabinoids may help treat various skin conditions.

Targeting TGFβ can improve skin immunity in older people.

Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.

IL-3 worsens lupus nephritis and blocking it improves kidney health.

Adipokines affect skin health and could be targeted for treating skin diseases.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

High DHA levels delay wound healing and worsen skin repair quality.

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.

Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.

PRP helps skin heal, possibly through special cells called telocytes.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.