15 citations,
August 2006 in “Journal of Cutaneous Pathology” HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.
15 citations,
September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
15 citations,
October 1970 in “Archives of disease in childhood” Hair amino acid levels can indicate metabolic disorders.
14 citations,
May 2021 in “Marine Drugs” PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.
14 citations,
February 2021 in “Experimental Dermatology” Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
14 citations,
October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
14 citations,
June 2018 in “Frontiers in pharmacology” Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.
14 citations,
January 2018 in “Scientific reports” Bioluminescence imaging can track hair follicle cells and help study hair regrowth.
14 citations,
February 2017 in “Scientific Reports” Certain variations of the HDAC9 gene can increase or decrease stroke risk in the Chinese population.
14 citations,
January 2017 in “Elsevier eBooks” CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.
14 citations,
October 2016 in “Psychoneuroendocrinology” Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
14 citations,
January 2016 in “Biochemical and Biophysical Research Communications” Ginsenoside Re from ginseng may help hair grow by blocking a specific growth-inhibiting pathway.
14 citations,
September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
14 citations,
April 2011 in “Cell Proliferation” Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
14 citations,
January 2008 in “Gene therapy” Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.
13 citations,
January 2021 in “RSC chemical biology” Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
13 citations,
November 2013 in “Seizure: European Journal of Epilepsy” Levetiracetam may cause hair loss, which can potentially reverse with lower doses or stopping the drug.
13 citations,
December 2001 in “Dermatologic therapy” Alopecia areata causes varying hair loss patterns, affecting hair, nails, and possibly glands, with treatment outcomes depending on disease duration and extent.
12 citations,
August 2022 in “Stem cell reviews and reports” Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.
12 citations,
July 2021 in “Scientific Reports” Glutamic acid helps increase hair growth in mice.
12 citations,
June 2021 in “Scientific Reports” Curcumin may help reverse aging by targeting specific genes.
12 citations,
February 2021 in “Translational Psychiatry” Researchers found two new genetic variants linked to Alzheimer's disease.
12 citations,
November 2020 in “Journal of Dermatological Science” Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
12 citations,
August 2019 in “BMC Medical Genetics” Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.
12 citations,
May 2017 in “Pharmacology & therapeutics” Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.
11 citations,
September 2021 in “Journal of molecular endocrinology” ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
11 citations,
May 2021 in “Dermatologic clinics” PRP and cell therapies may help with hair loss, but more research is needed.
11 citations,
February 2018 in “Amino acids” Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
11 citations,
July 2016 in “Endocrinology” Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.
11 citations,
January 2016 in “Journal of clinical & experimental dermatology research” Substance abuse can cause various skin problems, including marks from injections, sores, premature aging, and increased cancer risk.