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    Glossary Neuroinflammation

    inflammation of nervous tissue involving immune cell activation

    Neuroinflammation refers to the inflammation of the nervous tissue, which can occur in the brain or spinal cord. It is typically a response to infection, injury, or disease and involves the activation of immune cells within the central nervous system. This process can contribute to various neurological conditions, such as multiple sclerosis, Alzheimer's disease, and even some forms of alopecia, where the immune response may inadvertently target hair follicles.

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    Research 30 of 548

    1. Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition Psychoneuroendocrinology · 2018 · 37 citations
    2. Direct implantation of hair-follicle-associated pluripotent (HAP) stem cells repairs intracerebral hemorrhage and reduces neuroinflammation in mouse model PloS one · 2023 · 3 citations
    3. Androgenic modulation of arterial baroreceptor dysfunction and neuroinflammation in endotoxic male rats Brain Research · 2021 · 2 citations
    4. Anti-Amnesia-like Effect of Pinus densiflora Extract by Improving Apoptosis and Neuroinflammation on Trimethyltin-Induced ICR Mice International journal of molecular sciences · 2023
    5. Protein Kinase C Downregulation upon Rapamycin Treatment Attenuates Neuroinflammation and Mitochondrial Disease Innovation in aging · 2020
    6. Cardiac and brainstem neuroinflammatory pathways account for androgenic incitement of cardiovascular and autonomic manifestations in endotoxic male rats Journal of Cardiovascular Pharmacology · 2021 · 1 citations
    7. Cardiac and Medullary Neuroinflammatory Pathways Trigger Androgenic Incitement of Cardiovascular Sequels of Endotoxemia in Rats The FASEB Journal · 2020
    8. Mechanisms underlying select chemotherapeutic-agent-induced neuroinflammation and subsequent neurodegeneration European Journal of Pharmacology · 2018 · 21 citations
    9. Microalgae extract induces antidepressant-like activity via neuroinflammation regulation and enhances the neurotransmitter system Food and Chemical Toxicology · 2022 · 11 citations
    10. LINCS Dataset-Based Repositioning of Dutasteride as an Anti-Neuroinflammation Agent Brain Sciences · 2021 · 6 citations
    11. Immunomodulatory Effects of Platelet-Rich Plasma (PRP) on Neuroinflammation: Insights from B92 Glial Cells Stimulated with Heat-Killed Escherichia coli 2025
    12. 5α-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat Brain Behavior and Immunity · 2016 · 47 citations
    13. Sex differences in steroid levels and steroidogenesis in the nervous system: Physiopathological role Frontiers in Neuroendocrinology · 2019 · 35 citations
    14. Neurosteroids and Epileptogenesis Journal of Neuroendocrinology · 2013 · 19 citations
    15. Mitochondria Dysfunction and Inflammation in Traumatic Brain Injury: Androgens to the Battlefront Androgens · 2021 · 9 citations
    16. Combined drug triads for synergic neuroprotection in retinal degeneration Biomedicine & pharmacotherapy · 2022 · 6 citations
    17. The role of sleep in telogen effluvium and trichodynia: A commentary in the context of the current pandemic Journal of Cosmetic Dermatology · 2021 · 6 citations
    18. Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications Toxins · 2022 · 5 citations
    19. TSPO ligand etifoxine attenuates LPS-induced cognitive dysfunction in mice Brain Research Bulletin · 2020 · 5 citations
    20. The connection of 5-alpha reductase inhibitors to the development of depression Biomedicine & Pharmacotherapy · 2021 · 4 citations
    21. Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy Neuroscience Letters · 2022 · 3 citations
    22. Bipolar Patients and Bullous Pemphigoid after Risperidone Long-Acting Injectable: A Case Report and a Review of the Literature Brain Sciences · 2021 · 3 citations
    23. Acetate meliorates depressive-like behaviour in a rat model of PCOS through suppression of HDAC2 expression and DNA methylation Research Square (Research Square) · 2022 · 1 citations
    24. Exploration of the Possible Relationships Between Gut and Hypothalamic Inflammation and Allopregnanolone: Preclinical Findings in a Post-Finasteride Rat Model. PubMed · 2025
    25. Assessment of Vascular Circulation in Alopecia Areata Using the FMSF Technique Journal of Clinical Medicine · 2025
    26. EFFECT OF FINASTERIDE TREATMENT IN MALE RAT: DEPRESSIVE-LIKE BEHAVIOR AND RELATED PARAMETERS 2019
    27. Immunosenescence and inflammaging in Parkinson’s disease: mechanisms and therapeutic prospects Frontiers in Immunology · 2026
    28. Peripheral MC1R Activation Modulates Immune Responses and is Neuroprotective in a Mouse Model of Parkinson’s Disease Journal of Neuroimmune Pharmacology · 2023 · 9 citations
    29. Exosomes in stroke management: A promising paradigm shift in stroke therapy Neural Regeneration Research · 2024 · 2 citations
    30. Peripheral Neuroprotective and Immunomodulatory Effects of 5α-Reductase Inhibitors in Parkinson’s Disease Models Frontiers in Pharmacology · 2022 · 1 citations