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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.

Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.

Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.

Most women with depression in the study had low vitamin D levels.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

Finasteride use may lead to less alcohol consumption in men with lasting sexual side effects.

Finasteride can cause sexual problems and depression in young men.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Finasteride for hair loss increases risk of long-lasting sexual dysfunction.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.

Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Myristoleic acid helps hair growth by boosting cell growth and recycling processes in hair follicle cells.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Finasteride may cause side effects; more research needed.

A new method accurately measures amino acids in treated hair, showing bleaching reduces amino acids while protein treatments increase them.