research Effects of Oral Finasteride on Erectile Function in a Rat Model
Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.
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research Irradiation-Induced Hair Graying in Mice: An Experimental Model to Evaluate the Effectiveness of Interventions Targeting Oxidative Stress, DNA Damage Prevention, and Cellular Senescence
Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Positional Vertigo and Unilateral Gradual Hearing Loss Following Sleeve Gastrectomy: A Case Report
A woman experienced vertigo and hearing loss after weight loss surgery, possibly due to eustachian tube issues from fat loss around ear muscles.
research Application of Multi-Omics Techniques to Androgenetic Alopecia: Current Status and Perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Exogenous Testosterone, Finasteride, and Castration Effects on Testosterone, Insulin, Zinc, and Chromium in Adult Male Rats
Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.
research Sertolioma in a Canadian Husky: Relationship Between Tumor, Hormones, Neurons, and Skin
Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.
research Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity
Alopecia areata involves immune system imbalances that may lead to depression and anxiety.
research The Effect of Finasteride on the Male Rat Brain
Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.
research The Murine Hair Follicle Is a Melatonin Target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Melatonin
Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
research Sex Differences in the Hypothalamic–Pituitary–Adrenal Axis’ Response to Stress: An Important Role for Gonadal Hormones
Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
research Pathophysiological Mechanisms Implicated in Postpartum Depression
Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.
research Lower Urinary Tract Symptoms: What’s New in Medical Treatment?
New drugs and combination therapies are improving treatment for lower urinary tract symptoms.
research Female Sexuality and Common Sexual Dysfunctions: Evaluation and Management in a Primary Care Setting
Primary care doctors should address female sexual dysfunctions to improve women's sexual health and life quality.
research Analysis of Androgen Receptor Expression and Activity in the Mouse Brain
Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.
research Impact of Estrogens in Males and Androgens in Females
Both estrogens and androgens are important for health in both males and females.
research GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects
GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
research Immunohistochemical Evaluation of Androgen Receptor and Nerve Structure Density in Human Prepuce from Patients with Persistent Sexual Side Effects after Finasteride Use for Androgenetic Alopecia
Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
research Total Facelift: Forehead Lift, Midface Lift, and Neck Lift
Facelifts for Asians are challenging due to thicker, heavier skin.
research The Role of Nrf2 in Hearing Loss
Activating Nrf2 can help protect against hearing loss.
research Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and Delta-Subunit-Containing Gamma-Aminobutyric Acid A Receptors
14,15-EET may help reduce poststroke pain by affecting certain brain proteins.
research Therapeutic Effects of Stem Cells in Different Body Systems: A Comprehensive Review
Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
research Direct Cellular Reprogramming Enables Development of Viral T Antigen-Driven Merkel Cell Carcinoma in Mice
Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
research Mechanical Stimulation of Human Hair Follicle Outer Root Sheath Cultures Activates Adjacent Sensory Neurons
Touching hair can activate nearby nerve cells through signals from the hair's outer layer.
research The Multisystem Impact of Long COVID: A Comprehensive Review
Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.
research A Proposed Etiopathology of Persistent Dysfunctions Emerging from Use and Discontinuation of 5-Alpha Reductase Inhibitors: Sequelae of Drug-Mediated Microvasculopathy
The document suggests that drugs for prostate issues might cause lasting sexual, mental, and physical health problems due to blood vessel damage in the penis.
research Combination of Media, Biomaterials, and Extracellular Matrix Proteins to Enhance the Differentiation of Neural Stem/Precursor Cells into Neurons
Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.
research ATP-Dependent Chromatin Remodeling During Mammalian Development
ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
research Platelet-Rich Plasma and Regenerative Dentistry
Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.