December 2021 in “Ad-Dawaa' Journal of Pharmaceutical Sciences” This study concluded that hair tonic formulations using extracts of green tea leaves, celery leaves, or their combination can effectively promote hair growth in guinea pigs, with the fastest growth seen using a 2.5% green tea to 7.5% celery leaf extract ratio.
7 citations
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December 2021 in “Annals of Phytomedicine An International Journal” This study observed that silver nanoparticles synthesized using Laurus nobilis leaf extracts significantly inhibited protein denaturation and membrane stabilization in vitro, suggesting potential as a basis for novel antiarthritic drugs.
December 2024 in “Ankara Universitesi Eczacilik Fakultesi Dergisi” This review highlights Nigella sativa L. (black cumin) as a plant with numerous health benefits, noting its rich nutritional profile and reported therapeutic effects such as antioxidant and anti-inflammatory activities, identified through various in vitro, in vivo, and clinical research studies.
January 2026 in “Journal of Applied Pharmaceutical Science” This study identified that the ethanol extract of Selaginella doederleinii may enhance the effectiveness of doxorubicin in treating cervical cancer cells while also providing chemopreventive benefits.
September 2019 in “Asian Journal of Pharmaceutical and Clinical Research” In this study, researchers found that the methanolic seed extract of Tectona grandis, known for its use in traditional medicine, demonstrated strong analgesic properties in Swiss albino mice, being effective at doses of 200–250 mg/kg and safe up to 1000 mg/kg.
November 2025 in “Discover Food” This study found that a catechins-rich Assam tea extract demonstrated antioxidant effects and hair growth promotion in mice, suggesting its potential as a natural alternative for treating hair loss.
5 citations
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July 1999 in “Journal of Anatomy” This study found that methylene blue staining may reveal anatomical details of intraepidermal nerve fibre endings in the rat mystacial pad with greater clarity than the zinc iodide-osmium tetroxide technique.
August 2026 in “Free Radical Biology and Medicine”
January 2017 in “Journal of Dermatology and Venereology” This study found that Naringenin and Hesperetin significantly increased the proliferation of hair-related cells and suggested potential as natural hair growth-promoting agents.
July 2026 in “Veterinary Medicine and Science” In this study, Quercetin-loaded black seed oil nanoemulsion effectively mitigated testosterone-induced testicular oxidative stress and inflammation in rats undergoing exercise and restraint stress, with improved antioxidant levels and reduced inflammatory markers compared to other treatment groups.
May 2024 in “Jurnal Lmu Farmasi dan Kesehatan/” In an experimental study, researchers evaluated shampoo formulations using celery leaf extract (Apium graveolens L) for hair growth and found that a 2% extract concentration provided the most favorable physical and chemical properties compared to other formulations.
August 2026 in “Revista Brasileira de Farmacognosia” Sea holly extract may help reduce hair loss.
2 citations
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December 2017 in “Bangladesh Journal of Pharmacology” In this study, N. sativa oil and decoction significantly protected against chemotherapy-induced alopecia in albino rats.
2 citations
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April 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that lotion containing ethanolic extract of Phyllanthus niruri and 1% menthol enhanced hair growth in white Wistar rats more than a formula without menthol, although not significantly.
February 2014 in “아시안뷰티화장품학술지” This review discusses various natural extracts, such as peppermint, rosemary, wild cultivated ginseng, and others, for their potential hair growth promotion effects and calls for further exploration into combinations with fewer side effects.
July 2024 in “Journal of Investigative Dermatology” In these two clinical trials, DS-2325a, a KLK5 inhibitor, was found to be generally safe and well tolerated in healthy volunteers, with mild and non-serious adverse events, suggesting its potential for further development as a treatment for Netherton Syndrome.
6 citations
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January 2009 This study found that topical application of Russelia equisetiformis methanol extract significantly increased hair growth in albino Wistar rats, potentially due to its triterpene and flavonoid content.
4 citations
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August 2022 in “The Scientific World Journal” This study found that bufotalinin, derived from Merremia peltata leaves, may enhance hair growth by acting as a potential androgen receptor antagonist in rabbits.
April 2023 in “Jurnal Farmasi Indonesia” In this study using New Zealand White rabbits, a nanoemulsion combining candlenut oil and celery powder improved hair growth over 28 days, showing greater hair weight and thickness than both positive and negative controls, suggesting potential as an alopecia treatment.
This study found that a complex extract of Polygonatum sibiricum and Nelumbinis semen improved menopause symptoms in an ovariectomized rat model by enhancing blood lipid metabolism and reducing osteoporosis, without increasing risks of side effects like endometriosis, unlike conventional hormone-replacement therapy.
4 citations
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December 2017 in “International journal of research in ayurveda and pharmacy” This review discusses the traditional and pharmacological uses of Cuscuta reflexa, but it reports no new clinical results, calling attention to its potential antihypertensive, antidiabetic, and antioxidant properties.
January 2016 in “Journal of chemical and pharmaceutical research” The study reported that both ethanol and water extracts of pakis munding roots significantly promoted hair growth in male rabbits, showing better results than the marketed hair growth drug minoxidil.
50 citations
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May 2011 in “Journal of Ethnopharmacology” In this cell study, Eclipta alba extract inhibited cancer cell proliferation and induced apoptosis, showing potential antiproliferative and anti-metastasis effects on liver and related cancer cell lines.
October 2025 in “Journal of Advances in Medical and Pharmaceutical Sciences” This study reported that Neelibhringadi Kera Tailam, a traditional Ayurvedic herbal oil, contains bioactive compounds that may support hair health by stimulating growth, providing antimicrobial, antioxidant, and anti-inflammatory effects, and preventing hair loss, as evidenced by its physicochemical, phytochemical, and GC-MS analyses.
9 citations
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December 2022 in “Antibiotics” This study found that coconut seed extract may effectively treat scabies in rabbits by improving infection signs and causing high mite mortality, suggesting its potential as a cost-effective herbal alternative.
April 2025 in “International Journal For Multidisciplinary Research” This study formulated a nano-herbal hair spray using neem, fenugreek, and amla extracts combined with chitosan nanoparticles, finding it enhanced hair elasticity, breakage resistance, and provided antibacterial protection, suggesting it as an effective natural alternative to traditional hair treatments.
April 2019 in “Agriculture and natural resources” October 2023 in “Indonesian Journal of Biomedicine and Health Science” In this study, researchers found that a combination of celery and candlenut extracts significantly increased hair length in male Wistar rats, while hair weight increased with either extract alone or combined, and hair thickness was most improved with candlenut extract alone.
January 2018 in “BiblioBoard Library Catalog (Open Research Library)”
February 2026 in “International Journal of Molecular Sciences” This study investigated the photoprotective properties of Brazilian pepper tree extract against UV-induced damage in skin cells, reporting that it enhanced expression of genes relevant to skin health and showed superior activity compared to standard antioxidants.