Acute Toxicity Studies and Evaluation of Analgesic Property of Tectona Grandis Methanolic Seed Extract in Swiss Albino Mice

The study from September 20, 2019, examined the safety and pain-relieving effects of Tectona grandis (teak) methanolic seed extract in Swiss albino mice. The extract was deemed safe at a dose of 1000 mg/kg and showed significant analgesic effects at 200-250 mg/kg body weight, as evidenced by reduced pain response in acetic acid-induced writhing, tail flick, and tail immersion tests. The pain-relieving properties were likely due to bioactive compounds such as flavonoids, xanthones, and glycosides found in the extract. However, the number of mice used in the study was not mentioned in the document.