October 2025 in “International Journal of Research in Dermatology” This review highlights the benefits of long-pulsed Nd:YAG lasers for hair removal in individuals with Fitzpatrick skin types IV-VI, offering deeper follicular targeting with reduced melanin interaction, and examines emerging technologies like radiofrequency and RF microneedling for safe treatment options in skin of color.
April 2024 in “Lasers in medical science” This study reviews the use of lasers and light therapies as treatment options for managing the two most common types of alopecia—androegenetic alopecia and alopecia areata—highlighting that existing FDA-approved drugs like minoxidil and finasteride are partially effective, necessitating additional therapeutic approaches.
January 2024 in “Dermatologic therapy” This review describes the characteristics and treatment of acne keloidalis nuchae, focusing on related conditions and available therapeutic approaches, but presents no new clinical findings.
April 2023 in “Journal of The American Academy of Dermatology” This letter discusses findings from an article by Sun et al. showing that neodymium doped yttrium aluminum garnet laser effectively treats prominent facial vasculature in patients with frontal fibrosing alopecia, but highlights concerns about the risk of iatrogenic scarring and suggests caution with treatment frequency.
July 2021 in “British Journal of Dermatology” Laser treatment for skin conditions VEN and ILVEN is effective and liked by patients.
May 2019 in “Pakistan Journal of Pharmaceutical Sciences” This study investigated the effects of 10600nm CO2 dot laser and Nd: YAG laser on Wistar rats' skin, finding that CO2 laser treatment resulted in higher positive expression of MMP-1 and TIMP-1 compared to Nd: YAG laser, with statistically significant differences noted.
January 2018 in “Springer eBooks” This review discusses the factors affecting laser hair removal results and adverse events, emphasizing the need for more research to determine optimal treatment parameters; it reports no new clinical findings.
May 2017 in “Journal of The American Academy of Dermatology” Combining microneedling with Q-switched laser treatment for tattoo removal did not improve results and caused more pain.
April 2017 in “Journal of Investigative Dermatology” This study observed that using a 1064 nm Nd: YAG laser may stabilize hair loss and promote new growth in some females with frontal fibrosing alopecia, though individual results varied.
September 2016 in “Journal of dermatological science” In this study, transplanted whisker follicles from ND-GFP mice aided spinal cord repair in injured mice, and surprisingly, also grew long hair shafts at the site of transplantation.
May 2015 in “Journal of The American Academy of Dermatology” Laser treatment is safe and can effectively treat toenail fungus, especially when combined with other treatments if no improvement is seen after about a year.
This study of hirsutism in Chennai found idiopathic causes most common and reported that both Nd YAG and IPL lasers had a 70% good response rate in hair removal across different skin types.
March 2012 in “Journal of the American Academy of Dermatology” African Americans lack knowledge about laser hair removal safety, Nd:Yag laser treatment is effective with high satisfaction, pressure during surgery can cause hair loss, and treating ovarian inflammation may help with alopecia areata.
July 2026 in “International Journal of Drug Delivery Technology” This review highlights novel drug delivery systems for alopecia that enhance localization in the pilosebaceous unit, reduce systemic exposure, and support sustained drug release, with a focus on optimized follicular carriers ranging from 100-300 nm for improved drug residence compared to conventional methods.
January 2026 in “Frontiers in Cellular Neuroscience” This study discusses the complex roles and effects of brain-synthesized sex neurosteroids, highlighting sex differences in their concentrations and their varied impacts on synaptic plasticity, cognitive behavior, and aging-related cognitive decline.
December 2024 in “PLoS ONE” In this study, researchers evaluated male-pattern hair loss treatments using RNA and microRNA expression profiling in 91 male participants, identifying 52 differentially expressed genes and suggesting a potential role for personalized treatment based on genetic analysis to monitor and predict treatment efficacy and compliance.
June 2020 in “Journal of Investigative Dermatology” This study reports that extracellular microvesicles isolated from stimulated dermal fibroblasts enhanced hair follicle growth ex vivo and identified norrin as a novel modulator in hair regeneration processes.
April 2018 in “Journal of Investigative Dermatology” This study found that ERBB2 mutations and amplifications are likely key drivers of extramammary Paget disease, suggesting potential for targeted therapies and cancer immunotherapy due to the moderately high mutational load observed.
28 citations
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September 2019 in “International Journal of Nanomedicine” This study found that minoxidil nanoparticles increased drug delivery to hair follicles and improved hair growth more effectively in mice than conventional minoxidil formulations.
16 citations
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October 1994 in “The Journal of Steroid Biochemistry and Molecular Biology” Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
May 2025 in “Antioxidants” This review highlights how natural products with antioxidant properties can modulate the Wnt signaling pathway, potentially influencing various pathological conditions such as cancer, stroke, and regenerative medicine. It also addresses controversies in the compounds' mechanisms across different models and suggests research directions for future studies.
36 citations
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March 2019 in “European Journal of Human Genetics” This study found genetic variations, including de novo variants and copy number variations, that may be associated with phenotypic discordance in monozygotic twins with various clinical conditions.
2 citations
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October 2024 in “PubMed” The authors reviewed nine studies on various dermatological procedures for treating Seborrheic Dermatitis, noting significant efficacy in small cohorts with high patient satisfaction, but highlighted the need for further research to address challenges like cost, variable effectiveness, and long-term safety.
1 citations
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January 2015 in “Journal of Pigmentary Disorders” This article reviews melasma in men, its causes, and treatment options, but reports no new clinical findings.
August 2025 in “Journal of Cosmetic Dermatology” In this systematic review, researchers examined various treatments for axillary hyperpigmentation, finding that Q-switched Nd:YAG laser and intense pulsed light showed significant improvement with minimal adverse effects; desonide and Cyperus rotundus oil were also notably effective among topical treatments.
September 2024 in “Journal of Drugs in Dermatology” This review found that various dermatological procedures for Seborrheic Dermatitis, such as phototherapy and laser treatments, showed significant efficacy in small cohorts with high patient satisfaction, but highlighted the need for further research to standardize protocols and evaluate long-term outcomes.
1 citations
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January 2023 in “Metabolites” This review discusses the relationship between gut microbiota and polycystic ovarian syndrome (PCOS), including its potential mechanisms and the role of alterations in microbiome composition on PCOS pathophysiology.
68 citations
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July 2016 in “Dermatology and Therapy” This review highlights that light and laser therapies, such as the 1064-nm Nd:YAG and 810-nm diode lasers, may offer significant improvement for acne keloidalis nuchae with minimal side effects, though larger trials are needed.
November 2023 in “Cosmetics” This study evaluated the protective effects of a hair conditioner containing rice derivatives on natural Caucasian hair using various analysis methods and found that the conditioner, especially with rice germ oil GX-N, effectively improved hair properties even under stress conditions like irradiation.
9 citations
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December 2023 in “Journal of Neuroimmune Pharmacology” This study found that systemic administration of NDP-MSH, a melanocortin receptor agonist, provided neuroprotective effects on dopaminergic nigrostriatal neurons in a mouse model of Parkinson's disease, reducing neuroinflammation and suggesting a role for regulatory T cells in these neuroprotective effects.