Reduction in the Free Androgen Index in Overweight Women After Sixty Days of a Low Glycemic Diet

    January 2024 in “ Experimental and clinical endocrinology & diabetes ”
    Barbara Zapała, Patrycja Marszalec, Monika Piwowar, Olaf Chmura, Tomasz Milewicz
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    TLDR A low-glycemic diet improved hormone levels and well-being in overweight women with high androgen levels.
    The study involved 44 overweight and obese women diagnosed with hyperandrogenism, a common endocrine disorder in women that can lead to symptoms such as hirsutism, acne, and alopecia. The research found that a low-glycemic index diet with anti-inflammatory elements and a slight energy deficit led to decreased total testosterone levels (p<0.003), increased sex hormone-binding globulin (SHBG) levels (p<0.001), and decreased the free androgen index (FAI; p<0.001). Post-intervention, participants reported higher overall well-being and reduced stress (p<0.001). The study concluded that in overweight and obese women, a properly selected diet, moderate physical activity, and reduction in weight, stress factors, and alcohol consumption can lead to several positive effects, including reduced FAI and symptoms such as acne, hirsutism, menstrual disorders, and infertility.
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