48 citations
,
November 1992 in “International Journal of Dermatology” This article discusses the history and terminology of toxic epidermal necrolysis but reports no new clinical results.
January 2021 in “Journal of cosmetology & trichology” This study suggests that L-(+)-Tartaric Acid may support hair growth by up-regulating certain genes in human Dermal Papilla cells, making it a potentially useful additive in minoxidil formulations.
2 citations
,
December 2018 in “Natural Product Research” This study identified a new compound from fermented Carica papaya L. with moderate antioxidant and potent hair growth-stimulating activities in vitro.
November 2025 in “Journal of Investigative Dermatology”
February 2025 in “Journal of Ayurveda and Integrated Medical Sciences” This study explores the use of Neem oil and a sesame oil-based formulation in Ayurvedic treatments for hair loss, suggesting their potential to improve scalp health, nourish hair follicles, and balance doshas, thereby aiding in hair loss prevention and management.
29 citations
,
January 2020 in “BioMed Research International” This study found that sinapic acid promotes the browning of 3T3-L1 adipocytes and may offer therapeutic potential for obesity by influencing mitochondrial biogenesis through the p38 MAPK/CREB signaling pathway.
8 citations
,
August 2022 in “Pharmaceutics” This study found that erythrocyte-anchored CPA-encapsulated nanoparticles improved the delivery and accumulation of Cepharanthine in the lungs, enhancing its effectiveness in treating acute lung injury by reducing inflammatory responses.
In this study, topical latanoprost acid applied daily for 6 months increased hair count and improved trichoscopic markers among women with hair loss, suggesting its potential for treating female androgenetic alopecia, particularly at a 0.05% concentration.
20 citations
,
April 2020 in “Journal of advanced Biomedical and Pharmaceutical Sciences” This study investigated the use of methylene blue in a niosomal hydrogel for photodynamic treatment of acne and found that it led to significant improvement in inflammation compared to IPL treatment.
This study investigated the phytochemicals in Phyla nodiflora leaf extracts and identified n-Hexadecanoic acid, stigmasterol, and beta-sitosterol as promising drug candidates for diabetes, alopecia, cancer, and anti-diuresis, advocating further research into these compounds.
December 2023 in “FUDMA Journal of Sciences” In this study, researchers analyzed Vachellia nilotica and Senegalia ataxacantha from Katsina state, Nigeria, identifying various bioactive compounds in their shoots and suggesting their potential as raw materials for pharmaceutical antifungal therapies.
January 2026 in “Annals of Clinical Endocrinology and Metabolism” This narrative review summarizes evidence on NAD⁺ biosynthesis and turnover, highlighting that while NAD⁺ precursors like NR and NMN consistently boost NAD⁺ levels in preclinical and human studies, clinical outcome results remain varied, indicating a need for more standardized human trials.
December 2019 in “International journal of scientific research in science and technology” This study developed and validated a simple and cost-effective spectrophotometric method to accurately determine Aminexil in cosmetic formulations containing niacinamide and pyridoxine.
April 2015 in “The FASEB Journal” In this study, NM exposure in mouse skin disrupted pilosebaceous units, initially decreasing markers of sebum production and cellular division, but showed signs of healing and marker recovery by day five.
April 2025 in “Pharmaceuticals” This study found that novel thiol-reactive cross-linking agents, particularly APA, significantly improved the tensile strength and elasticity of human hair fibers by effectively regenerating disulfide bridges, with potential applications for advanced hair repair treatments in the cosmetic industry.
December 2024 in “Journal of Pakistan Association of Dermatologists” This study found that in treating mild to moderate acne vulgaris, topical tazarotene 0.1% was more effective than topical adapalene 0.1%, with 100% of patients using tazarotene achieving the desired outcome compared to 75.3% in the adapalene group.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that tofacitinib may inhibit CD8+ T cell infiltration in alopecia areata by affecting the linoleic acid metabolism-Mg2+ pathway in a sodium sulfide-induced mouse model, highlighting new insights for clinical diagnosis and treatment strategies.
May 2004 in “International Journal of Cosmetic Science” This study found that kojic acid and niacinamide were the most effective inhibitors of UVB-induced NF-κB activation and IL-6 secretion in HaCaT keratinocytes, suggesting a role in modulating melanotrophic factor synthesis.
21 citations
,
December 2014 in “Clinics in dermatology” This review discusses squaric acid dibutylester's use, effects, and safety in treating alopecia areata, but reports no new clinical results.
24 citations
,
January 2003 in “Journal of Investigative Dermatology” In this study, a synthetic antagonist of the p75 neurotrophin receptor was found to significantly inhibit hair follicle regression in murine skin cultures, suggesting a potential role in treating hair disorders characterized by premature catagen entry.
7 citations
,
September 2024 in “PLANT PHYSIOLOGY” This study in Arabidopsis thaliana found that exposure to volatile compounds from Penicillium aurantiogriseum promotes root hair growth through signaling involving RALF22, ethylene, auxin, and photosynthesis, and that RALF22 plays a crucial role in the plants' response to these compounds.
April 2017 in “Journal of Investigative Dermatology” In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.
4 citations
,
January 1993 in “Clinical Chemistry and Laboratory Medicine (CCLM)” This study developed a highly sensitive fluorescent assay for measuring enzyme activity in single hair follicles, allowing the efficient analysis of over 100 samples per day.
1 citations
,
June 2018 in “International Journal of Dermatology” DNCB is highly effective for treating alopecia areata with minimal long-term side effects.
27 citations
,
August 2017 in “Anais Brasileiros de Dermatologia” In this case report, a patient with trichotillomania showed a significant positive response to treatment with N-acetylcysteine, suggesting its potential effectiveness for this disorder according to the authors’ observations.
3 citations
,
January 1993 in “Toxicological Sciences” This study found that 2-ethylhexanoic acid impaired fertility in Wistar rats and delayed postnatal development of pups, suggesting potential reproductive toxicity at certain dosages.
October 2025 in “Journal of Advances in Medical and Pharmaceutical Sciences” This study reported that Neelibhringadi Kera Tailam, a traditional Ayurvedic herbal oil, contains bioactive compounds that may support hair health by stimulating growth, providing antimicrobial, antioxidant, and anti-inflammatory effects, and preventing hair loss, as evidenced by its physicochemical, phytochemical, and GC-MS analyses.
August 2002 in “Analytical Sciences” The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.
June 2023 in “International Journal of Clinical Research and Reports” This study found that higher concentrations of topical diphenylcyclopropenone, especially when prepared with acetone, showed better stability over 6 months compared to lower concentrations.
February 2025 in “Journal of Nanobiotechnology” This study developed a microneedle system using black phosphorus nanosheets and baicalin for treating androgenetic alopecia, finding it effectively enhanced drug penetration and follicular targeting while showing synergistic efficacy and safety in preclinical tests, including in vivo model efficacy against testosterone-induced hair loss.