Trichotillomania: A Good Response to Treatment with N-Acetylcysteine

    August 2017 in “ Anais Brasileiros de Dermatologia ”
    Lívia Ariane Lopes Barroso, Flavia Sternberg, Maria Natalia Inacio de Fraia e Souza, Gisele Jacobino de Barros Nunes
    TLDR N-acetylcysteine effectively treats trichotillomania.
    Trichotillomania, a behavioral disorder characterized by hair-pulling leading to alopecia, affected 1% of adults and 2-4.4% of psychiatric patients, with higher prevalence in adolescents and females. The condition often involved the scalp, eyebrows, and eyelashes. N-acetylcysteine, a glutamate modulating agent, showed promise as a treatment by reducing oxidative stress and normalizing glutaminergic transmission. The paper reported a case where trichotillomania responded excellently to N-acetylcysteine treatment.
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