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This review explores the application of nanotechnology in cosmetics, highlighting its role in enhancing skin penetration, sustaining drug action, and protecting against UV radiation, while also addressing regulatory considerations and potential exposure routes.

This review highlights recent advancements in using niosomes as nanocarriers for improved delivery and sustained release of active cosmetic compounds, discussing their properties, applications, and future potential in cosmetic chemistry.

This study found that dissolving microneedle array patches containing mesoporous silica nanoparticles can deliver antigen-loaded nanoparticles into mice effectively, inducing strong immune responses similar to traditional subcutaneous injection.

This study introduced ElixirSeeker2, a computational framework for designing anti-aging peptides, and found that some newly identified peptides significantly delayed cellular senescence and enhanced cellular and locomotor functions in aged Caenorhabditis elegans.

This research developed a zinc-doped nanocomposite using biodegradable materials, observing effective bone targeting and regeneration capabilities in vivo, with no observed cytotoxicity in the MG63 cell line, potentially due to blocking Farnesyl Diphosphate Synthetase to inhibit osteoclastic activity and promote osteogenesis.

This review discusses the transformation of selenium nanoparticles into multifunctional platforms for skin disease treatment, focusing on engineering principles rather than their intrinsic bioactivity alone, and reports no new clinical results.

This review discusses the challenges and contradictions in understanding nanoparticle penetration and toxicity in human skin, emphasizing the need for standardized testing and further research on particles smaller than 10 nm.

This study found that a nanobiotechnological method may allow express diagnostics of ocular adnexal tumors by comparing the level of biogenic silver nanoparticle formation between malignant and benign tumors.

This study found that topical application of nano-Zinc oxide in newborn mice led to the accumulation of nanoparticles within hair follicles, inducing apoptosis of hair follicle stem cells and potentially disrupting skin homeostasis.

This chapter reviews nanotechnology in cosmetics, detailing various formulations, performance assessment methods, and evolving regulations, while discussing safety, stability, and effectiveness concerns; it reports no new experimental results.

This review focuses on recent advances in smart responsive polymer microneedles, which offer precise, on-demand drug delivery triggered by external or physiological stimuli, highlighting significant research implications for transdermal drug administration according to this source.

In this study, silver oxide-based nanoparticles were used to ionize analytes and detect specific target molecules through adduct formation with silver isotopes, facilitating signal correlation with these molecules.

This study reports that a new boron/nitrogen-doped carbon nano-onion-based delivery system for doxorubicin enhanced its uptake and anticancer effects in specific cancer cell types, while reducing cardiotoxicity in human heart cells.

This review discusses the design and advances of lipid–polymer hybrid nanoparticles as promising delivery systems for genome editing strategies, highlighting their potential in biomedical applications.

This study used advanced optical imaging techniques to investigate nanoparticle and dye penetration in human skin, finding that nanoparticles mainly resided in the stratum corneum and accumulated in skin folds and hair follicles, while highlighting that sunscreen-based nanoparticles appear unlikely to pose safety concerns.

This publication presents a library of geometric medicines designed to selectively target pathogenic bacteria and fungi with high precision while minimizing ecological harm, available for free on a non-commercial basis.

This article explores the potential of chitin nanofibrils as a bioactive polymer for skin applications by examining their hydrophilic properties and effects on cell behavior, but presents no new experimental results.

In this study, researchers developed hollow mesoporous organosilica nanoparticles and confirmed their synthesis using IR spectroscopy, then evaluated the nanoparticles for endocytosis and biocompatibility, although specific results of these tests are not reported in the abstract.

Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.

This study reports that a novel ketoconazole-loaded microneedle array significantly enhances drug delivery and retention in the skin, demonstrating improved hair growth in animal models, suggesting a promising treatment for androgenic alopecia that addresses current topical therapies' limitations.

This study found that niosomal aminexil was more clinically effective for hair growth than conventional aminexil solutions, and that niosomes facilitated aminexil penetration through rat skin without propylene glycol.

This study found that transdermal delivery of finasteride using biomimetic Platycladi cacumen-derived nanovesicles enhanced hair regrowth in a mouse model of androgenetic alopecia, outperforming minoxidil by improving skin permeation, reducing oxidative stress, and boosting local drug retention.

The researchers developed semi-dissolving microneedle patches using TEMPO-oxidized bacterial cellulose nanofibers, which allow effective transdermal drug delivery by forming micro-channels for large drug quantities, overcoming traditional microneedles' low drug loading.

This study developed a delivery platform using hyaluronic acid-based dissolvable microneedles with nanoliposomes containing kopexil and kopyrrol, which showed improved hair regeneration for treating androgenetic alopecia in vivo at lower dosages compared to minoxidil.

In this study, researchers developed ionizable coenzyme Q10-engineered lipid/fiber microplexes that restored mitochondrial-ribosomal function and enhanced mRNA translation in senescent cells, leading to increased hair follicle density and bone formation in mouse models compared to conventional lipid nanoparticles.

In this study, silver nanoparticles prepared using Ziziphus nummularia fruit extract showed higher hair growth activity and were more effective against Gram-positive bacteria compared to other extracts.

This narrative review suggests that nanoformulated phytochemicals hold promise for managing polycystic ovarian syndrome, but their efficacy and safety compared to standard treatments require further validation through clinical studies.

Niosomes are a promising and effective way to deliver drugs through the skin.

This study demonstrated that a light-activated RNAi approach using hollow gold nanoshells effectively targets human prostate cancer cells with reduced off-target toxicity and material use compared to standard methods.

In this study, researchers developed a near-infrared-responsive nanoplatform that synergistically enhances chronic wound healing by accelerating mitochondrial restoration and immune modulation, leading to enhanced wound repair and high-quality healing in diabetic rat models.