Cutaneously Applied Nano-ZnO Reduces the Ability of Hair Follicle Stem Cells to Differentiate

    March 2017 in “ Nanotoxicology ”
    Wei Ge, Yong Zhao, Fang-Nong Lai … Wei Shen
    Studysummary This study found that topical application of nano-Zinc oxide in newborn mice led to the accumulation of nanoparticles within hair follicles, inducing apoptosis of hair follicle stem cells and potentially disrupting skin homeostasis.
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    Research cited in this study 4

    1. Human Hair Follicle: Reservoir Function and Selective Targeting British Journal of Dermatology · 2011
    2. Follicular Transport Route: Research Progress and Future Perspectives European journal of pharmaceutics and biopharmaceutics · 2009
    3. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    4. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000