April 2024 in “Research Square (Research Square)” This case report describes a 27-year-old male with autoimmune polyglandular syndrome type 1, characterized by symptoms including fever, dysarthria, dysphagia, oral candidiasis, nail dystrophy, alopecia, hypoparathyroidism, and dilated cardiomyopathy. The study highlights unique bilateral symmetrical brain calcifications and underscores the syndrome’s diverse manifestations.
March 2024 in “IP Indian journal of clinical and experimental dermatology” In this study conducted at a tertiary care center, rural elderly patients often exhibited skin conditions like wrinkling, generalized pruritus, xerosis, eczematous skin conditions, and psoriasis, highlighting the need for better health education on skin care, early diagnosis, and management.
October 2023 in “Dermatology practical & conceptual” This study found that pulse corticosteroids effectively induce hair regrowth in alopecia areata, with betamethasone showing higher efficacy but more side effects, and treatment success varying depending on age, onset time, and disease type.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
October 2023 in “TURKDERM” This study observed a 30.4% decrease in dermatology outpatient visits during the COVID-19 pandemic, with a shift in patient demographics and an increased frequency of psoriasis, bullous diseases, and melanoma diagnoses, while conditions like acne and xerosis cutis were less frequent.
September 2023 in “Journal of Cosmetic Dermatology” This study concluded that topical minoxidil could effectively accelerate nail growth in both healthy individuals and those with nail disorders, though the regimen might differ across these groups.
This study found significant correlations between scalp and nail involvement and laboratory findings in Korean patients with chronic cutaneous lupus erythematosus, highlighting their importance for diagnosis and management.
May 2022 in “Rossijskij žurnal kožnyh i veneričeskih boleznej” This paper reviews the complexity of nest alopecia's causes and associations, noting chronicity, recurrence, and associations with comorbid conditions, and presents two clinical cases, but reports no new quantitative findings.
December 2021 in “Trichology and cosmetology:” This study demonstrated that a daily oral supplement of 1000 mg Kera-Diet® improved hair and nail conditions in women experiencing acute telogen effluvium and brittle nail syndrome over three months.
October 2021 in “Dermatology Reports” This study found that serum IL-17A levels were significantly higher in patients with alopecia areata compared to healthy controls and correlated with disease severity and activity.
January 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified non-structural proteins in preschool children's scalp hair that suggest potential biomarkers for brain development, immune function, and stress response with heritability and age-related differences.
September 2019 in “Journal of Investigative Dermatology” This study found that a history of smoking significantly predicted a more refractory course of palmoplantar pustulosis, with associated comorbidities often including hypertension, type 2 diabetes mellitus, and thyroid diseases.
May 2018 in “Dermatologic Surgery” This overview details the Dermatologic Surgery journal's focus on various dermatologic surgical procedures, but it presents no new research findings.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
January 2017 in “IMC Journal of Medical Science” This case report describes a 26-year-old man from Bangladesh diagnosed with autoimmune polyendocrine syndrome type 1, a rare endocrine disorder involving adrenocortical insufficiency, hypoparathyroidism, and mucocutaneous candidiasis.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
December 2016 in “Journal of evolution of medical and dental sciences” This study reported common skin changes and symptoms associated with thyroid disorders, such as dry skin in hypothyroidism and warm, soft skin in hyperthyroidism, and noted urticaria as a frequent autoimmune association in hypothyroid patients.
September 2015 in “Actas Dermo-Sifiliográficas” This review covers skin manifestations in chronic kidney disease, highlighting their impact on quality of life, associated prognostic indicators, and available treatments, but provides no new clinical results.
Iron supplements may reverse premature graying in iron-deficient individuals; ingrown nails are common in diabetics with certain risk factors; topical finasteride may reduce scalp DHT as effectively as oral finasteride; monilethrix treatment is challenging but some medications can help.
February 2010 in “Journal of The American Academy of Dermatology” A woman's nail separation was likely caused by poor blood flow, and a treatment for similar conditions might help.
June 1997 in “Australasian Journal of Dermatology” This article discusses hair and nail research contributions in dermatology but reports no new clinical findings.
January 1993 in “Side effects of drugs annual” This chapter covers various dermatological drugs, cosmetics, and topical agents, focusing on the properties and uses of propolis, but does not present new clinical findings.
September 2016 in “Journal of dermatological science” This study found that COL17 plays a key role in regulating epidermal keratinocyte differentiation and proliferation, influencing the expression of differentiation markers and cellular growth in specific conditions.
7 citations
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July 2019 in “Advances in preventive medicine” Among 255 subjects with diabetes, this study found an 88.4% prevalence of skin conditions and 15.7% prevalence of nail manifestations, linked with factors like age and disease duration.
February 2026 in “Clinical Drug Investigation” In this study, patients with severe alopecia areata who were treated with baricitinib 4 mg/day for 48 weeks showed significant improvements in both hair regrowth and nail abnormalities, although the correlation between hair and nail improvement was weak.
854 citations
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February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This review summarizes recent advances in understanding the molecular mechanisms of hair follicle formation and discusses potential future clinical applications for treating hair loss and skin tumors, but it reports no new clinical results.
359 citations
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” This article reviews the role of skin appendages in wound healing and appendage regeneration, discussing cellular and molecular mechanisms but reports no new experimental findings.
65 citations
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March 2018 in “Journal of Dermatological Science” This review discusses the role of mechanical forces in skin homeostasis and disease development, including their impact on conditions like keloids, androgenetic alopecia, and acral melanoma, and reports no clinical results; the authors propose modifying these forces as a potential therapeutic strategy.
41 citations
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January 2018 in “Advances in experimental medicine and biology”
35 citations
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April 2008 in “Human Molecular Genetics” This review discusses advances in using molecular tools from skin biology to manipulate adult stem cells for regenerative medicine and reports no new clinical results.