Peculiarities of Clinical Course and Diagnosis of Alopecia Areata with Comorbidity: Clinical Observations

Alopecia areata, characterized by circular baldness, often has a chronic and recurrent course, with spontaneous remission possible in 50% of cases. The disease is influenced by neurotrophic, autoimmune, genetic, and endocrine factors, and is frequently accompanied by nail plate damage. The study highlights the need for more research on nail involvement and emphasizes the importance of tailored diagnostic and therapeutic approaches due to the complexity added by comorbid conditions like systemic lupus erythematosus, psoriasis, and vitiligo. Two clinical cases are discussed: one involving a child with anemia, chronic gastrointestinal diseases, and celiac disease, and another involving an adult with anemia, thyroiditis, gastrointestinal diseases, and post-COVID syndrome.