TLDR Alopecia areata is complex, often recurring, and needs personalized treatment, especially with other health issues.
Alopecia areata, characterized by circular baldness, often has a chronic and recurrent course, with spontaneous remission possible in 50% of cases. The disease is influenced by neurotrophic, autoimmune, genetic, and endocrine factors, and is frequently accompanied by nail plate damage. The study highlights the need for more research on nail involvement and emphasizes the importance of tailored diagnostic and therapeutic approaches due to the complexity added by comorbid conditions like systemic lupus erythematosus, psoriasis, and vitiligo. Two clinical cases are discussed: one involving a child with anemia, chronic gastrointestinal diseases, and celiac disease, and another involving an adult with anemia, thyroiditis, gastrointestinal diseases, and post-COVID syndrome.
31 citations,
July 2021 in “ImmunoTargets and therapy” Alopecia areata is an incurable autoimmune condition causing hair loss, with research aiming for better treatments.
2 citations,
June 2021 in “Медицинский совет” Hair loss from coronavirus can be treated.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
20 citations,
August 2018 in “Clinics in Dermatology” The conclusion is that understanding and addressing the psychological effects of alopecia areata is important for effective treatment.
74 citations,
May 2016 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics” Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.
62 citations,
January 2015 in “Journal of Dermatological Science” New genetic discoveries may lead to better treatments for alopecia areata.
391 citations,
January 2010 in “Journal of The American Academy of Dermatology” Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
6 citations,
March 2019 in “JAAD case reports” A new mix of anthralin and calcipotriene might help treat severe hair loss.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
