Efficacy and Adverse Effects of Corticosteroid Pulse Therapy in Alopecia Areata

    October 2023 in “ Dermatology practical & conceptual ”
    Fatemeh Rastaghi, Roxana Kaveh, Nazafarin Yazdanpanah, Akram-Sadat Sahaf, Najmeh Ahramiyanpour
    Image of study
    TLDR Pulse corticosteroids help regrow hair in alopecia areata but have side effects, especially betamethasone.
    Pulse corticosteroids are effective in inducing hair regrowth in alopecia areata (AA), with betamethasone being the most effective but also having more side effects. The efficacy and relapse rates of pulse corticosteroid therapy depend on factors such as the time of AA onset, age, and type of AA. Recent onset, younger age, and multifocal type are associated with better outcomes and lower relapse rates. Patients with a history of atopy, nail pitting, thyroid disease, or severe forms of AA show the least improvement. Combining corticosteroids with other medications can reduce dosage and side effects, with prednisolone and methylprednisolone being safer but less effective options.
    Discuss this study in the Community →

    Research cited in this study

    21 / 21 results

    Related Community Posts Join

    6 / 63 results

      community Betnovate Scalp for hair loss?

      in Product  2 upvotes 1 year ago
      A dermatologist prescribed Betnovate scalp, a corticosteroid, for a 21-year-old male's hair loss due to DHT. The individual is considering using Nizoral shampoo, topical finasteride, a derma roller, and minoxidil, but is unsure about the effectiveness of two other products suggested by the dermatologist.

      community formula 82D for diffuse androgenic alopecia (DUPA)

      in Is this regrowth?  16 upvotes 1 month ago
      The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.

      community Best places to get clobetasol?

      in Product  1 upvotes 1 month ago
      The user is considering switching to oral dutasteride, topical minoxidil, retinoic acid, and clobetasol for hair loss treatment, after limited regrowth with finasteride and other topicals. They are seeking a source for clobetasol, as they believe it may help with their condition.

      community Is hydrocortisone that bad for your scalp?

      in Minoxidil  1 upvotes 2 months ago
      Hydrocortisone is not recommended for long-term use on the scalp due to potential side effects like thinning and steroid-related issues. Alternatives like foam minoxidil or oral minoxidil are suggested, though foam may be less effective.

      community I’ve read multiple times that Fin increases hair quality… NOT for me!

      in Treatment  97 upvotes 1 year ago
      A user has been on finasteride for 6 months and feels their hair quality has worsened, experiencing more hair loss and scalp irritation. They are considering seeing a dermatologist, while others suggest the issue might be unrelated to finasteride, possibly due to deficiencies or other conditions.

    Related Research

    4 / 4 results