12 citations
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March 2021 in “JAAD Case Reports” This study reported that immunotherapy in cancer patients can lead to skin-related immune adverse events, such as rashes, pruritus, and vitiligo, affecting a substantial proportion of patients.
10 citations
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January 2013 in “Faṣlnāmah-i bīmārīhā-yi pūst” This study found no significant association between vitamin D levels and alopecia areata in patients when gender was accounted for, but vitamin D levels were lower in patients with nail involvement.
9 citations
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March 2015 in “International reviews of immunology” This review discusses the relationship between ectodermal alterations and immunodeficiencies, particularly the roles of hyper-IgE syndrome, ectodermal dysplasia, and FOXN1 gene mutations, but it presents no new research findings.
9 citations
,
April 2006 in “American Journal of Pathology” This study found that mutations in the Sgk3 gene cause defective hair follicle development and altered hair cycling in mice, with variable phenotypic outcomes depending on different dysfunction patterns of the SGK3 protein.
8 citations
,
March 2015 in “Neuromuscular Disorders” This study found that adult patients with Myotonic Dystrophy type 1 exhibited a higher prevalence of various morphofunctional, inflammatory, and proliferative skin disorders compared to healthy controls.
7 citations
,
June 2021 in “JAAD Case Reports” This article reviews the cutaneous manifestations of COVID-19, highlighting their potential as early indicators of infection, and reports no new clinical results.
7 citations
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March 2018 in “Journal of The American Academy of Dermatology” This study found that pediatric HSCT recipients, especially those with chronic graft-versus-host disease, are at risk for developing various nonmalignant late cutaneous changes such as vitiligo, psoriasis, alopecia, and nail changes.
6 citations
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January 2012 in “Journal of Biomedicine and Biotechnology” This report reviews peer-reviewed case studies indicating potential efficacy of ustekinumab for treating challenging forms of psoriasis but notes the need for further research on cost-effectiveness and risk-benefit.
5 citations
,
September 2015 in “BMC Medical Genetics” In this study, individuals with a c.1072C > T mutation in the EDAR gene showed more hair shaft deformations compared to non-mutation carriers, highlighting EDAR's role in hair follicle development.
4 citations
,
January 2025 in “Diagnostics” This article reviews the use of high-frequency ultrasonography to visualize nail units and scalps in dermatology, highlighting its potential benefits for disease assessment and treatment monitoring, but reports no new clinical results.
4 citations
,
December 2020 in “Mammalian genome” This study found that pelage abnormalities in Harlequin mutant mice are linked to severe AIF deficiency and associated with altered expression of genes related to hair structure.
4 citations
,
March 2017 in “Journal of evolution of medical and dental sciences” This study observed that pruritus and xerosis were the most common skin complaints among the geriatric population attending a dermatology clinic in Puducherry.
4 citations
,
January 2016 in “Dermatology Review” This review focuses on the various skin toxicities caused by chemotherapeutic and targeted tumor therapy drugs, including rashes, keratoacanthoma, and more severe conditions like Stevens-Johnson syndrome, without presenting new clinical results.
3 citations
,
July 2017 in “Elsevier eBooks” This article reviews the identification and assessment of cutaneous drug reactions, emphasizing the importance of early recognition and the need for accurate diagnosis to prevent serious complications; it reports no new clinical results.
2 citations
,
May 2025 in “Frontiers in Pharmacology” In this study, analysis of FDA data revealed a substantial risk of dermatologic adverse events with aromatase inhibitors, especially anastrozole and exemestane, highlighting the importance of dermatologic monitoring during such therapies.
2 citations
,
October 2016 This article discusses the range of skin-related side effects caused by chemotherapy and radiotherapy, including novel patterns emerging with targeted therapies, but does not report new clinical results.
2 citations
,
February 2014 in “Hair therapy & transplantation” This article reviews the autoimmune mechanism and potential environmental triggers of alopecia areata, focusing on cytokines, but does not provide new research findings.
1 citations
,
November 2023 in “Curēus” This case report describes a young male with trachyonychia with associated hypertrophic cutaneous lichen planus, reticular oral lichen planus, and nail lichen planus. The diagnosis was aided by dermoscopy and histopathology, highlighting the importance of accurate diagnosis for effective treatment and prognosis.
1 citations
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February 2020 in “International Journal of Research in Dermatology” This study describes the clinical profile of scalp alopecia areata among patients at a tertiary care hospital, finding it more common in males, particularly those aged 21-30, with sudden onset and often asymptomatic progression.
1 citations
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January 2019 in “Przegla̧d dermatologiczny” This article reviews the concept of cardiodermatology and its application in clinical practice but does not present new empirical findings.
1 citations
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January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
1 citations
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September 2005 in “Oncology times” In this study, wearing a frozen glove during docetaxel chemotherapy reduced nail problems in patients' gloved hands compared to unprotected hands, with onycholysis absent among protected hands.
May 2026 in “Research Square” This research reports that the polyG fragment within the Hoxc13 protein alters its gene regulatory functions, which could have influenced mammalian hair evolution by affecting pathways related to hair follicle development.
March 2026 in “Nature Communications” In this study, researchers conducted a large genome-wide association meta-analysis and found 30 significant genetic loci linked to the risk of dermatophytosis, shedding light on the roles of keratin biology, skin barrier defects, immune dysfunction, and obesity in the disease.
February 2026 in “JEADV Clinical Practice” This review discusses the causes of nail pitting in children and adolescents, noting that while most cases are idiopathic, significant associations exist with conditions like psoriasis, juvenile arthritis, and alopecia areata, among others.
January 2026 in “Journal of Biosciences and Medicines” This research highlights the common and varied skin-related symptoms associated with chronic kidney disease, emphasizing that early recognition and multi-pronged management involving nephrology and dermatology can improve patient outcomes.
July 2025 in “Berkala Ilmu Kesehatan Kulit dan Kelamin” This study described the clinical characteristics of 18 pediatric patients with alopecia areata at a hospital in Denpasar from 2021 to 2023, finding equal gender distribution and hair loss as the most common symptom, with onset typically within 1–6 months.
In this clinical trial, the researchers observed that a biotin and silica supplement reduced hair fall, increased hair growth rate, and improved skin elasticity, hydration, and nail quality over 90 days without adverse effects.
March 2025 in “Dermatology” Systemic therapies improve nail psoriasis but have high side effects; more research is needed.
October 2024 in “La Tunisie Médicale” In this cross-sectional study conducted at Farhat Hached Hospital in Tunisia, more than half of the 60 alopecia areata patients surveyed experienced depression, particularly younger individuals and those with severe or specific forms of the condition, underscoring the need for psychological support.