research The Utility of Metformin Therapy in Reproductive-Aged Women with Polycystic Ovary Syndrome
Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
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research In Vivo and In Vitro Exposure to Free Fatty Acids Induce Increased Androgen Production in Animal Models: A Potential Pathogenic Factor of Polycystic Ovary Syndrome
Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.
research Both Lesional and Non-Lesional Skin from Acne Patients Shows Robust IL-17-Skewing and Upregulation of Antimicrobial Peptides
Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.
research Androgenic Alopecia: Pathogenetic Mechanisms and Therapeutic Approaches
The document concludes that current treatments for androgenic alopecia are not fully effective, but new therapies like botulinum toxin and PRP show promise, and future gene therapy could be beneficial.
research Aging and Colony-Forming Efficiency of Human Hair Follicle Keratinocytes
Aging reduces the ability of human hair follicle cells to form new cell colonies.
research Botanical Treatment for Polycystic Ovary Syndrome
Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.
research Plant Biomass Materials in Cosmetic Application
Plant biomass materials are effective and eco-friendly for skin and hair care in cosmetics.
research IL-17C: Checkpoint in Innate Skin Immunology
IL-17C is important in inflammatory skin diseases and could be a target for treatment.
research Importance of Isolated Gestational Hypothyroxinemia in the Development of Obstetric and Somatic Pathologies
Pregnant women with isolated hypothyroxinemia face more health issues, so iodine and folic acid supplements are important before and during early pregnancy.
research Evaluation of a Novel Hybrid Polymer in Hair Treatment
The new polymer improves dyed hair's color, moisture, shine, and smoothness.
research PPAR-γ Modulation as a Novel Therapeutic Strategy for Scarring Alopecia
A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.
research N-Terminal Functional Domain of Gasdermin A3 Regulates Mitochondrial Homeostasis via Mitochondrial Targeting
Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
research Prognostic Factors in the Treatment of Androgenetic Alopecia with Minoxidil
Minoxidil works better for hair regrowth if you have higher SULT1A1 enzyme activity and ATP concentration.
research The Role of Metabolic Syndrome in the Development of Polycystic Ovary Syndrome in Adolescence
Preventing childhood obesity can reduce the risk of developing polycystic ovary syndrome in adolescents.
research Acquired Progressive Kinking of the Hair in a Prepubertal Boy
A 10-year-old boy had the earliest reported case of hair that became progressively kinkier but eventually returned to normal on its own.
research A Review of the Clinical and Histopathological Characteristics of Patients with Subepidermal Blistering Disorders Presenting to a Tertiary Care Centre in India
Most patients with blistering skin disorders in South India had bullous pemphigoid and often had other conditions like hypertension and diabetes.
research Investigating the Role of Mef2c in Hair Follicle Cycling
MEF2C is crucial for normal hair cycle progression.
![Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase](/images/research/d19df8a7-8de6-4430-8a0d-4ffa1f502985/small/15608.jpg)
research Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase
New compounds were made that effectively block a specific enzyme related to androgen conditions.
research Endocrinology and Auxology of Siblings with Non-Classical Congenital Adrenal Hyperplasia
Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.
research Serenoa Repens and N-Acetyl Glucosamine/Milk Proteins Complex Differentially Affect the Paracrine Communication Between Endothelial and Follicle Dermal Papilla Cells
Serenoa repens and N-acetyl glucosamine/milk proteins complex may help with hair growth and prevent hair loss.
research Particulate Matter 2.5 Damages Skin Cells by Inducing Oxidative Stress, Subcellular Organelle Dysfunction, and Apoptosis
Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
research Hair-Pulling Disorder
New treatments for hair-pulling disorder focus on personalized approaches and combining therapies for better results.
research The Efficacy of 1550-nm Erbium-Glass Fractional Laser Treatment and Its Effect on the Expression of Insulin-Like Growth Factor 1 and Wnt/β-Catenin in Androgenetic Alopecia
Finasteride helps female-pattern hair loss.
research Development of the Emulsion for the Androgenic Alopecia Treatment
The emulgel with specific ingredients was effective for treating hair loss.
research Induction of Transforming Growth Factor-Beta 1 by Androgen Is Mediated by Reactive Oxygen Species in Hair Follicle Dermal Papilla Cells
Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
research In Vivo Hair Growth Stimulating Activity of Ethanol Extract and Its Fractions from Rampai Lampung (Lycopersicon Esculentum Mill.) Leaves
Rampai leaves extract can significantly stimulate hair growth.
research Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice
Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.
research Thymic Peptides Differentially Modulate Human Hair Follicle Growth
Some thymic peptides can increase human hair growth, while others may inhibit it.
research Significance of Psychosomatic Factors in the Etiopathogenesis of Alopecia Areata
Psychological factors play a significant role in developing alopecia areata.
research Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.