January 2026 in “Cutaneous and Ocular Toxicology” This study found that Yangxuebushen Decoction significantly promoted hair regrowth and improved hair follicle structure in a cyclophosphamide-induced alopecia mouse model by reducing inflammation, oxidative stress, and apoptosis.
July 2025 in “Colloids and Surfaces B Biointerfaces” This study found that the new delivery system HL@Mi enhanced the skin penetration, local bioavailability, and safety of minoxidil, supporting improved hair growth in an androgenetic alopecia animal model.
8 citations
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January 2011 in “Collection of Czechoslovak Chemical Communications” This study developed and validated a sensitive method using adsorptive cathodic stripping voltammetry to directly determine minoxidil in topical solutions, shampoos, and creams, achieving high recovery rates and precision.
17 citations
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June 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that mice with a Cx43 mutation exhibited slower and asynchronous hair regrowth with severe cuticle weathering, mimicking aspects of hair phenotype in some ODDD patients.
January 1999 in “American Journal of Medical Genetics Part A” This case report describes a rare occurrence of ectodermal dysplasia features in a 14-year-old with MBTPS1 gene variants, expanding the known spectrum of related disorders.
23 citations
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January 2016 in “Theranostics” In this animal study, ultrasound combined with a new microbubble formulation of minoxidil increased hair growth rates and improved follicle characteristics more effectively than minoxidil alone.
11 citations
,
December 2015 in “Indian journal of dermatology, venereology, and leprology” Dermoscopy quickly and accurately diagnosed a rare hair disorder in a 12-year-old girl.
23 citations
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January 2011 in “International Journal of Immunopathology and Pharmacology” In this small study, topical minoxidil 2% was associated with an increase in normal hair shaft production in patients with Monilethrix without any reported side effects.
8 citations
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September 2016 in “Pediatric dermatology” This review discusses the diverse clinical manifestations of mucopolysaccharidoses in children and emphasizes the importance of early diagnosis and treatment initiation, but it reports no new clinical findings.
5 citations
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January 2018 in “Javma-journal of The American Veterinary Medical Association” This case report documents the first successful management of accidental minoxidil toxicosis in a dog, resulting in full recovery after treatment with supportive care, including medications for blood pressure and potential toxicity mitigation.
3 citations
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January 2002 in “Actas Dermo-Sifiliográficas” In this case report, a 23-year-old woman developed localized trichorrhexis nodosa after compulsively applying 3% minoxidil to her scalp for two months.
80 citations
,
August 1991 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This study found that low-dose methotrexate significantly reduced the steroid requirement in subjects with corticosteroid-requiring asthma without altering their clinical status or causing significant complications.
5 citations
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January 2021 in “Daru” This case report highlights a rare instance of severe multi-organ involvement following a single dose of methotrexate for ectopic pregnancy, requiring intensive care but ultimately successfully treated with leucovorin and supportive care.
5 citations
,
March 2016 in “Medical journal, Armed Forces India” This report describes a case of refractory shock and pulmonary edema resulting from the accidental ingestion of topical minoxidil, highlighting a rare instance of poisoning.
15 citations
,
June 2019 in “Biochemical Journal” This study identified a heterozygous de novo mutation in the ODC1 gene causing a new disorder characterized by overgrowth and developmental delay, and suggests that DFMO treatment may help manage elevated ODC activity and putrescine levels.
July 2026 in “Journal of the American Academy of Dermatology” 10 citations
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July 2014 in “Annals of Saudi Medicine” This case report describes a rare concurrence of Morbihan disease with eyelid edema and extrafacial lupus miliaris disseminatus faciei in a patient, noting improvement of truncal lesions with roxithromycin and resolution of eyelid edema following surgical treatment.
January 2024 in “JAAD case reports” This study discusses zinc's vital role in skin cell growth and how its deficiency can lead to acrodermatitis enteropathica, marked by symptoms like alopecia and dermatitis. It notes that similar symptoms appear in people with certain metabolic conditions, referred to as acrodermatitis dysmetabolica.
39 citations
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September 2018 in “American Journal of Medical Genetics Part A” This case report describes a 32-month-old girl with a newly identified pediatric disorder linked to a de novo mutation in the ODC1 gene, mirroring symptoms seen in a transgenic mouse model.
July 2021 in “Indian journal of drugs in dermatology” In this study, the combination of intradermal meso-solution and topical 5% minoxidil significantly increased hair re-growth in men with androgenetic alopecia compared to minoxidil alone.
6 citations
,
October 2011 in “Archives de pédiatrie” This case report describes a young girl who experienced vasoplegic shock and prolonged tachycardia after ingesting hair lotion containing minoxidil, highlighting the need for extended monitoring due to potential persistent hemodynamic issues.
11 citations
,
February 1982 in “Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis” This study reports that treatment with X-rays or procarbazine induced dose-dependent mutations in melanocytes in mouse hair follicles, showing similar mutation rates to previous methods.
December 2010 in “대한미용학회지” This study found that Polygoni multiflori Radix water extracts stimulated hair growth and hair follicle development in mice, suggesting it may be safer than minoxidil.
December 2009 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study found that iontophoresis significantly increased the retention of minoxidil sulfate in hair follicles, potentially improving drug delivery for androgenic alopecia treatment.
3 citations
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June 2019 in “Veterinary record case reports” This case report describes a miniature dachshund with pustular dermatitis and other symptoms, developing pemphigus foliaceus after receiving afoxolaner, which was effectively managed with prednisone and cyclosporine.
January 2011 in “Dialnet (Universidad de la Rioja)” This study found that the "After Minoxidil" spray improved hair styling and decreased greasiness after using topical minoxidil, which may enhance compliance and effectiveness.
2 citations
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May 2022 in “Advanced therapeutics” This study reported that a novel vasodilator drug called TOP-M119, when delivered using a specially designed dissolving microneedle system, showed enhanced targeting of hair follicles and effectiveness in treating alopecia, demonstrated through in vitro, ex vivo, and in vivo studies involving mouse skin.
June 2025 in “ACS Biomaterials Science & Engineering” In this study, researchers developed a new microneedle patch delivery system for minoxidil, which enhanced its controlled release and improved hair growth in mice, potentially offering better treatment outcomes for androgenetic alopecia.
May 2024 in “Australasian journal of dermatology” This study reports on a unique clinical presentation of folliculotropic mycosis fungoides in a 60-year-old man, highlighting complexities in diagnosis due to dense histiocytic infiltration, which led to xanthoma formation before treatment, and obscured lymphomatous features.
June 2013 in “Annals of the rheumatic diseases” This study concluded that while methotrexate-related adverse events were infrequent in early rheumatoid arthritis patients taking adalimumab, some increased with higher methotrexate doses, suggesting use of the lowest effective dose.