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Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Probiotic bacteria improved skin and hair health in aged mice.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.