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Surgical face-lifts are more effective, but fractional radiofrequency is a good, less invasive alternative for treating skin laxity.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

Epidermal nevi are skin cell clusters linked to various syndromes.

Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.

Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.

Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Muscles can make their own androgens, which may help muscle growth.

Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

Thallium, mercury, selenium, and colchicine strongly cause hair loss.

Scalp cooling can help prevent hair loss from chemotherapy, but treatment should be tailored to the individual and more research is needed.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Tailored treatments for alopecia areata are recommended based on severity and patient needs.

Boreal caribou in northeastern British Columbia have significant health issues, including infections, tick infestations, and mineral deficiencies.

The document suggests a possible link between FAM111B gene mutations and increased cancer risk, particularly pancreatic cancer.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Using superficial temporal fascia helps prevent Frey syndrome after parotid surgery.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

The modified Crawford technique resulted in less lagophthalmos and better cosmetic outcomes for patients with lateral droop.

TLR4 is important in aging-related diseases and could be a new treatment target.

Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.