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Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Softer hydrogels help wounds heal better with less scarring.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Noggin is necessary to start the hair growth phase in skin after birth.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Dog skin with hair loss, when transplanted to mice, regrew hair, suggesting the hair loss cause is likely body-wide, not skin-specific.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Hair follicle regeneration needs special conditions and young cells.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Future research should focus on making bioengineered skin that completely restores all skin functions.

The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.

Scientists can now create skin with hair by reprogramming cells in wounds.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Fat-related cells are important for initiating hair growth.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.