Search
for

    Glossary MSX2

    gene involved in embryonic development and hair follicle formation

    MSX2, also known as Msh homeobox 2, is a gene that encodes a protein involved in the regulation of embryonic development and cell differentiation. It plays a crucial role in the formation of various tissues, including bones and hair follicles. Mutations in the MSX2 gene have been linked to conditions such as craniosynostosis, a disorder characterized by the premature fusion of skull bones, and alopecia, which is hair loss.

    Sort by

    Research 30 of 266

    1. Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation Nature genetics · 2000 · 694 citations
    2. Genetic interplays between Msx2 and Foxn1 are required for Notch1 expression and hair shaft differentiation Developmental Biology · 2008 · 67 citations
    3. Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly ˜The œAmerican journal of pathology · 2012 · 22 citations
    4. Msx2 Supports Epidermal Competency during Wound-Induced Hair Follicle Neogenesis Journal of Investigative Dermatology · 2018 · 19 citations
    5. Hairless down-regulates expression of Msx2 and its related target genes in hair follicles Journal of dermatological science · 2013 · 14 citations
    6. Regulation of feather follicle development and Msx2 gene SNP degradation in Hungarian white goose BMC Genomics · 2022 · 1 citations
    7. 026
Altered Skin Wound Healing in Homeobox Gene Msx-2 Knockout Mice Wound Repair and Regeneration · 2008
    8. Roles for Msx and Dlx homeoproteins in vertebrate development Gene · 2000 · 234 citations
    9. Epidermal Dysplasia and Abnormal Hair Follicles in Transgenic Mice Overexpressing Homeobox Gene MSX-2 Journal of Investigative Dermatology · 1999 · 49 citations
    10. Molecular Mechanisms Regulating Hair Follicle Development 2002 · 854 citations
    11. Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot Developmental biology · 2003 · 243 citations
    12. `Cyclic alopecia' in<i>Msx2</i>mutants: defects in hair cycling and hair shaft differentiation Development · 2002 · 158 citations
    13. Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling Cellular physiology and biochemistry · 2016 · 43 citations
    14. Gsdma3 is required for hair follicle differentiation in mice Biochemical and biophysical research communications · 2010 · 30 citations
    15. <i>Msx2</i> Prevents Stratified Squamous Epithelium Formation in the Enamel Organ Journal of Dental Research · 2018 · 18 citations
    16. The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development 2016 · 16 citations
    17. Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes 2021 · 11 citations
    18. Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response Scientific Reports · 2017 · 7 citations
    19. A single-cell transcriptomic atlas elucidates the hair cycle and apoptosis mechanisms in goat hair follicles Frontiers in Cell and Developmental Biology · 2025
    20. Differential expression of keratin and keratin associated proteins are linked with hair loss condition in spontaneously mutated inbred mice Biochemical and Biophysical Research Communications · 2024
    21. Differential expression of keratin and keratin associated proteins are linked with hair loss condition in spontaneously mutated inbred mice bioRxiv (Cold Spring Harbor Laboratory) · 2024
    22. DNCB 유발 피부염 생쥐에서 보스웰리아가 피부조직 모발주기 관련 유전자에 미치는 영향 대한미용학회지 · 2021
    23. Australian Hair and Wool Research Society Cutaneous Biology and Endocrinology Workshop Experimental Dermatology · 2003
    24. Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis Developmental dynamics · 1998 · 252 citations
    25. Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis Matrix Biology · 2016 · 19 citations
    26. Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats PLoS ONE · 2016 · 127 citations
    27. Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents Journal of Investigative Dermatology · 2007 · 127 citations
    28. Microarray analysis of androgenetic and senescent alopecia: Comparison of gene expression shows two distinct profiles Journal of Dermatological Science · 2013 · 27 citations
    29. Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells in vitro by Forming a Complex With Tcf4 and β-Catenin Frontiers in Cell and Developmental Biology · 2020 · 13 citations
    30. Hair in health and disease: an introduction Wageningen Academic Publishers eBooks · 2012 · 3 citations