Effects of Boswellia on Hair Cycle-Related Genes in Mice with DNCB-Induced Dermatitis

    January 2021 in “ 대한미용학회지 ”
    조선아, 류은미
    TLDR Boswellia may improve skin inflammation symptoms and positively influence hair growth in mice.
    The study investigated the effects of Boswellia on hair cycle-related genes in mice with DNCB-induced atopic dermatitis. Using 5-week-old male Balb/c mice, DNCB was applied to induce dermatitis, followed by Boswellia administration. Visual and histological analyses showed significant improvement in dermatitis symptoms and changes in the keratin layer and hair follicle shape. Transcriptional analysis revealed increased expression of genes such as Gprc5d, Msx2, Ptch2, Wnt10b, Dsg4, Kratap4-16, Hc16, Apcdox, and S21 mR in the Boswellia-treated group. The study concluded that Boswellia could improve dermatitis symptoms and potentially enhance hair cycle or growth impediments caused by dermatitis.
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