1 citations
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May 2026 in “Nature Communications” This study demonstrated that CD19-CAR T cell therapy may promote structural regeneration in the skin of systemic sclerosis patients, as evidenced by histological improvements and fibroblast population changes, suggesting its potential for tissue remodeling in fibrotic diseases.
10 citations
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September 2024 in “Neural Regeneration Research” This study found that using induced pluripotent stem cell-derived mesenchymal stem cells with acellular nerve allografts significantly improved axon regeneration and functional recovery in rats with sciatic nerve injuries, suggesting a promising approach for clinical nerve repair therapies.
September 2006 in “Dermatologic Surgery” This study reported that squamous cell carcinomas of the scalp can be extraordinarily aggressive, potentially metastasizing and causing death, highlighting the need for early diagnosis and careful treatment approaches.
109 citations
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April 1997 in “Archives of Dermatological Research” The researchers reported that mast cell and nerve fiber interactions in mouse skin are highly selective for nerve fiber types and vary depending on the hair cycle phase.
14 citations
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May 2013 in “Experimental Dermatology” This study found that the modified wash test was generally more effective than TrichoScan® for diagnosing hair loss, particularly telogen effluvium, though both methods showed only fair concordance with clinical diagnosis.
2 citations
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May 2024 in “European journal of medical research” This study found that a conditioned medium from human umbilical cord mesenchymal stem cells cultured in a gelatin sponge significantly enhanced hair growth and promoted skin angiogenesis in a mouse model, more effectively than a monolayer culture.
July 2012 in “European journal of cancer” This study demonstrated that switching aE-catenin to aT-catenin in murine skin substantially rescued hyperproliferative and pre-cancerous conditions, but led to partial baldness, indicating potential functional discrepancies.
20 citations
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September 2020 in “Journal of Translational Medicine” This overview highlights the exploration of mesenchymal stromal cells as potential treatments for COVID-19, noting their regenerative and immunomodulatory properties for reducing ARDS severity in critically ill patients, but it provides no new clinical results.
October 2024 in “Journal of the Endocrine Society” This case report highlighted a rare instance of Cushing's syndrome caused by ectopic ACTH from cervical cancer, demonstrating diagnostic challenges, treatment complexity, and high risks of morbidity and mortality, with less than 10 cases documented overall.
January 2016 in “Institutional Repositories DataBase (IRDB)” This study examined the expression of fatty acid transporters and binding proteins in mouse sebaceous glands and found that CD36 did not affect the localization of other related molecules.
In this study, conditional inactivation of the Mad2l1 SAC gene in mice led to aggressive and lethal acute lymphoblastic leukemia and hepatocellular carcinoma, demonstrating a link between chromosomal instability and cancer development.
67 citations
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November 2019 in “Nature Communications” This study demonstrated that a c-Kit-CreER-driven mouse model confirms melanocyte stem cells as a genuine source of melanoma, paralleling human melanoma in heterogeneity and gene signatures.
September 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study introduces the MHS Hair Restoration Protocol, a systems-biology model targeting hair follicle health through the gut-microbiome-endocannabinoidome axis and innovative topical treatments, emphasizing a holistic approach to pattern hair loss.
9 citations
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September 2022 in “Journal of Clinical Investigation” In this study, mouse models of 22q11.2 deletion syndrome showed that growth issues in small embryonic thymuses were linked to mesenchymal cells, which could be corrected by substituting with normal mesenchyme.
9 citations
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December 2023 in “Materials Today Bio” This study found that modified microcrystalline cellulose with citric and ascorbic acid demonstrated enhanced hemostatic properties and biocompatibility in vitro and in animal hemorrhage models.
30 citations
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August 2021 in “Oncogene” This study reports that miR-22 promotes cancer progression and metastasis by maintaining Wnt/β-catenin signaling and cancer stem cell function.
August 2024 in “International Journal of Molecular Sciences” In this animal study, researchers found that local administration of mesenchymal stem cell therapy improved hair regrowth and reduced local inflammatory cytokines in mice with Alopecia Areata, although systemic cytokine levels were unchanged.
3 citations
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January 2018 in “Food Science and Technology Research” This study found that 6-methylsulfinylhexyl isothiocyanate (6-MSITC) significantly promoted proliferation and upregulated specific mRNA levels in human dermal papilla cells, suggesting potential as a hair growth stimulant.
This study found that inhibiting the Mitochondrial Pyruvate Carrier in human scalp hair follicles caused metabolic stress that halted cell proliferation and disrupted key signaling pathways, with these effects partially reversed by an integrated stress response inhibitor.
November 2023 in “International surgery journal” In this case study, a 69-year-old male with a neck swelling was diagnosed with a trichilemmal cyst, highlighting the importance of complete surgical excision for lesions with proliferative or malignant potential.
62 citations
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December 1966 in “Endocrinology” This study observed that injecting mice with α-MSH resulted in black hair regrowth in shaved and plucked areas, suggesting a potential link to the agent darkening hair in animals with a specific pituitary tumor.
113 citations
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November 2017 in “Scientific Reports” This study found that treatment with mesenchymal stem cell extracellular vesicles enhanced hair growth in mice and stimulated dermal papilla cell activity and growth factor production in vitro.
September 2022 in “Indian Journal of Paediatric Dermatology” This case report documents the first confirmed mutation-proved instance of Clouston syndrome in a large Chinese-Malaysian family, linked to the c.263C>T (A88V) mutation in the GJB6 gene, with no available treatment but highlighting the importance of genetic counseling.
9 citations
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September 2022 in “Frontiers in Physics” This study found that Mueller Matrix microscopy can accurately identify, detect, and evaluate hair follicles in mouse skin tissue, suggesting its potential for skin structure research and dermatological applications.
January 2025 in “American Journal of Stem Cells” This review discusses the role of melanocyte stem cells in skin pigmentation and potential regenerative therapies, but reports no new clinical results.
October 2022 in “Hair Transplantation” This review discusses scalp micropigmentation for hair loss and scarring and reports no clinical results; the authors highlight its use as both a standalone and adjunct treatment.
14 citations
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January 2001 in “Current Treatment Options in Oncology” Treat limited stage small cell lung cancer with chemotherapy and radiation, and consider preventive brain radiation for better survival chances.
2 citations
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September 2022 in “Annals of Medicine and Surgery” The researchers reported a rare case of invasive cutaneous squamous cell carcinoma of the scalp extending into bone and dura mater, successfully treated with surgery and skin flap repair, without metastasis observed at three months.
26 citations
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February 1998 in “Chemico-Biological Interactions” This review discusses recent molecular biology advances in the human phenol sulfotransferase gene family and reports no new results; the authors highlight its relevance for studies of endogenous and xenobiotic metabolism.
14 citations
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February 2020 in “Scientific reports” This study found that telocytes in human scalp tissue were located around hair follicles and glands and may be involved in skin regeneration and homeostasis.