research Development and Progression of Alopecia in the Vitamin D Receptor Null Mouse
Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
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research Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo
Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.
research Human Hair Follicle Regeneration Following Amputation and Grafting into the Nude Mouse
Human hair follicles can regenerate after removal, but with low success rate.
research Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin
Topical oligonucleotide therapy targets hair follicles effectively.
research Promotion of Hair Growth by Ginseng Radix on Cultured Mouse Vibrissal Hair Follicles
Ginseng, especially red ginseng, helps hair grow by increasing blood flow and energy to hair roots.
research Scanning Electrochemical Microscopy of Iontophoretic Transport in Hairless Mouse Skin: Analysis of the Relative Contributions of Diffusion, Migration, and Electroosmosis to Transport in Hair Follicles
Hair follicles significantly enhance electroosmotic transport during iontophoresis.
research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata
MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
research More About X-Linked Testicular Feminization of the Mouse as a Noninducible (is) Mutation of a Regulatory Locus: 5α-Androstan-3α-17β-Diol as the True Inducer of Kidney Alcohol Dehydrogenase and β-Glucuronidase
A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
research Glucagon-Like Peptide-1 Receptor and Proglucagon Expression in Mouse Skin
Mice skin has components that could help with hair growth and might be used for diabetes treatment.
research Lanceolate Hair-J (LahJ): A Mouse Model for Human Hair Disorders
The Lanceolate hair-J mutation in mice mimics human hair disorders like Netherton's syndrome.
research Heterogeneity of ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin and in epidermal tumors
The study investigated the expression of ornithine decarboxylase (ODC) in mouse skin treated with the tumor promoter TPA. It was found that ODC expression was heterogeneous, with high levels predominantly in suprabasal cells around hair follicles shortly after TPA treatment. This expression was transient, disappearing within 16 to 24 hours, but persisted in some cells within benign papillomas a week after TPA application. Pretreatment with retinoic acid or cycloheximide inhibited ODC expression. The findings suggested that both normal and tumor tissues in mice exhibited varied ODC expression.
research Cidea Control of Lipid Storage and Secretion in Mouse and Human Sebaceous Glands
Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.
research Divergent Neuroactive Steroid Responses to Stress and Ethanol in Rat and Mouse Strains: Relevance for Human Studies
Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
research Ornithine decarboxylase activity in relation to DNA synthesis in mouse interfollicular epidermis and hair follicles
research Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model
Superoxide dismutase (SOD) can prevent hair graying in mice.
research Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin
Olive leaf compound oleuropein helps grow hair in mice.
research Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle
Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
research Expression and Function of Group IIE Phospholipase A2 in Mouse Skin
sPLA2-IIE is crucial for normal hair follicle structure and skin health.
research Hair Growth Activity of Crataegus Pinnatifida on C57BL/6 Mouse Model
Crataegus pinnatifida extract may help increase hair growth and thickness in mice.
research Serenoa Repens Extracts Promote Hair Regeneration and Repair of Hair Loss in Mouse Models by Activating TGF-β and Mitochondrial Signaling Pathway
Serenoa repens extract helps regrow hair and repair hair loss by activating certain cell growth pathways.
research Wnt1a Maintains Characteristics of Dermal Papilla Cells That Induce Mouse Hair Regeneration in a 3D Preculture System
Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
research Isoallopregnanolone Reduces Tic-Like Behaviors in the D1CT-7 Mouse Model of Tourette Syndrome
Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.
research Heterotypic Cell Contacts and Basal Lamina Morphology During Hair Follicle Development in the Mouse: A Light, Scanning, and Electron Microscopic Study at the Site of Tissue Interaction
Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.
research Stem Cells from Human Exfoliated Deciduous Teeth Promote Hair Regeneration in Mice
Baby teeth stem cells can help grow hair in mice.
research Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model
Superoxide dismutase (SOD) can prevent hair graying in mice.
research Restoration of Hair Growth with Topical Diphenylcyclopropenone in Mouse and Rat Models of Alopecia Areata
Topical diphencyprone helped regrow hair in mice and rats with a condition similar to human hair loss.
research Hair Follicle-Derived Mesenchymal Stem Cells Decrease Alopecia Areata Mouse Hair Loss and Reduce Inflammation Around the Hair Follicle
Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
research Short-Term Biomarkers of Cigarette Smoke Condensate Tumor Promoting Potential in Mouse Skin
The study investigated the effects of cigarette smoke condensates (CSCs) on mouse skin, focusing on hyperplasia and inflammation as short-term biomarkers of tumor promotion. Using a truncated initiation-promotion protocol, the research assessed epidermal thickness, proliferative index, and ornithine decarboxylase (ODC) expression after CSC application. Results showed that CSCs increased these markers, with partial reversibility in interfollicular areas but sustained elevation in perifollicular regions. The study highlighted perifollicular ODC expression as a promising indicator for evaluating CSCs due to its rapid induction, low threshold, and potential to reflect irreversible changes, aligning with the notion that ODC expression is crucial for tumor promotion and that tumors primarily originate in the perifollicular epidermis.
research Topical Spermine And Putrescine Stimulated DNA Synthesis In The Hairless Mouse Epidermis
Topical putrescine and spermine increased DNA synthesis in hairless mouse skin.
research Jagged1 and Epidermal Growth Factor Promoted Androgen-Suppressed Mouse Hair Growth In Vitro and In Vivo
Jagged1 and Epidermal Growth Factor together significantly increased hair growth in mice with androgen-suppressed hair.