research CAQ Corner: Basic Concepts of Transplant Immunology
The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
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870-900 / 1000+ results research Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research Saponins of Paris Polyphylla for the Improvement of Acne: Anti-Inflammatory, Antibacterial, Antioxidant and Immunomodulatory Effects
Paris polyphylla saponins may effectively treat acne due to their antibacterial and anti-inflammatory properties.
research The Complex Relationship Between TFEB Transcription Factor Phosphorylation and Subcellular Localization
Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.
research Lipid Signaling in Keratinocytes: Lipin-1 Plays a Part
Lipin-1 is important for skin cell differentiation and skin barrier function.
research BRAF Inhibitor Dabrafenib in Patients with Metastatic BRAF-Mutant Thyroid Cancer
Dabrafenib was effective and well tolerated in treating thyroid cancer with a specific mutation.
research Anticancer Effects of Metformin on Neuroendocrine Tumor Cells In Vitro
Metformin may help treat neuroendocrine tumors.
research Aging Hair Follicles Rejuvenated by Transplantation to a Young Subcutaneous Environment
Old hair follicles grew better when moved to a young environment.
research Vitamin D And Skin Diseases: A Review
Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.
research The Force Is Strong with This One: Metabolism Overpowers Stem Cell Fate
Metabolism plays a key role in determining stem cell fate.
research Poly(rC) Binding Protein 2 Acts as a Negative Regulator of IRES-Mediated Translation of Hr mRNA
A protein called PCBP2 controls the production of a hair growth protein by interacting with its genetic message and is linked to hair loss when this control is disrupted.
research Plumbagin, A Natural Compound With Several Biological Effects And Anti-Inflammatory Properties
Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.
research The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators, and Myostatin Inhibitors
Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.
research Autophagy Induces Hair Follicle Stem Cell Activation and Hair Follicle Regeneration by Regulating Glycolysis
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
research Innovative Approach for Polycystic Ovary Syndrome Treatment: Brown Adipose Tissue
Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.
research The Potential of Regulatory T Cell-Based Therapies for Alopecia Areata
Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.
research Metformin and Malignant Tumors: Not Over the Hill
Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.
research Epilepsy and Neurodegeneration: Clues in the Hair and Blood Vessels
The document concludes that specific hair and blood vessel abnormalities in infants with seizures and developmental issues may indicate Menkes disease, which lacks a cure and is often fatal by age 3.
research AB1511 SLE Onset Post COVID-19 Vaccination: Coincidental or Association?
It's unclear if COVID-19 vaccination causes SLE; more research is needed.
research Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology
Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
research Induction of Dark Keratinocytes by 12-O-Tetradecanoyl-Phorbol-13-Acetate and Mezerein as an Indicator of Tumor-Promoting Efficiency
TPA is about 50 times more effective at promoting tumors than MZ.
research Androgen Modulation of Wnt/β-Catenin Signaling in Androgenetic Alopecia
Androgens may block hair growth signals, targeting this could treat hair loss.
research Finasteride Attenuates Pathological Gambling in Patients With Parkinson's Disease
Finasteride reduces gambling symptoms in Parkinson's patients.
research Experiences with Parieto-Occipital Flaps in Hair Transplantation
Using a scalp flap for hair transplantation gives denser, faster results than older methods, but it's complex and needs careful planning.
research Next-Generation Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.
research Fibroblast Heterogeneity and Tertiary Lymphoid Tissues in the Kidney
Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
research Secretory Phospholipase A2-IIA Overexpressing Mice Exhibit Cyclic Alopecia Mediated Through Aberrant Hair Shaft Differentiation and Impaired Wound Healing Response
Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
research Characterization of a Mouse Scube3 Reporter Line
Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.
research The Biology and Clinical Application of Systemic Glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement
Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.