6 citations
,
January 2017 in “Journal of toxicologic pathology” This study suggests that the patchy thickening and reddish discoloration in rabbit skin during the hair cycle may be due to large anagen-phase hair follicles compressing the dermis and increased blood vessels causing redness.
This study found that combining platelet-rich plasma injections with minoxidil in treating androgenetic alopecia increased the number of hair follicles, anagen phase hairs, and decreased telogen phase hairs compared to minoxidil alone.
53 citations
,
April 1985 in “Developmental Biology” Fibronectin and other basement membrane components increase during hair growth and decrease during rest.
92 citations
,
August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that newborn mouse skin organoids can robustly grow hair in vivo, while adult organoids require specific interventions to restore their hair-forming ability.
236 citations
,
July 2001 in “Trends in Molecular Medicine” This review discusses common hair loss conditions and explores how advancements in hair follicle biology might lead to more effective treatments but reports no new results.
January 2007 in “한국미용학회지” This study observed that in the telogen phase, hair roots from people with alopecia showed reduced fat tissues compared to ordinary people, suggesting a potential morphological marker for distinguishing hair conditions.
30 citations
,
May 2010 in “British Journal of Dermatology” This study found that intermediate hair follicles are morphologically distinct from terminal follicles and offer a novel model for developing new alopecia therapies despite being technically more challenging to study.
34 citations
,
December 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that rat vibrissa hair follicles cultured in vitro showed morphological changes suggesting cyclical activity but remained blocked in the pro-anagen stage.
48 citations
,
July 1993 in “Archives of Dermatological Research” Merkel cells are abundant in facial vellus hair follicles, especially during the anagen phase.
January 2007 in “한국미용학회지” This study found that a lack of fat tissues in the hair root during the telogen phase might indicate hair loss, potentially providing a standard for identifying hair conditions and the impact of cytotoxic drugs.
13 citations
,
February 2015 in “Actas Dermo-Sifiliográficas” This review discusses the histologic features of nonscarring alopecia and highlights the importance of clinical-pathological correlation for accurate diagnosis, but reports no new clinical results.
8 citations
,
July 2020 in “BMC genomics” In this study, ceruloplasmin and keratin 4 were identified as markers that differentiate between growing and resting phases in cashmere goat hair follicles, with keratin 4 being a potential marker for the onset of a new hair cycle.
46 citations
,
April 1971 in “American Journal of Clinical Nutrition” Lack of protein causes hair root damage, but it can be reversed by eating protein again.
40 citations
,
July 1989 in “Journal of Cell Science” This study found that while hair follicles can be viably maintained in vitro for 7 days, their morphology suggests a shift to the resting phase, likely due to isolation.
17 citations
,
November 1967 in “American Journal of Anatomy” This study observed that the catagen phase in hairless mice displayed a slower shortening of the mutant epithelial column, resulting in longer total follicle length and abnormalities in the connective tissue sheath and glassy membrane.
236 citations
,
January 1951 in “Physiological zoology” Hair growth and pigmentation in mice involve specific stages crucial for research.
134 citations
,
September 2008 in “Lasers in surgery and medicine” This study found that low fluence photoepilation with intense pulsed light targets the pigmented area of hair follicles, causing temporary hair loss by inducing a catagen-like state without severe follicle damage.
54 citations
,
July 1967 in “Science” This study found that aged tritiated thymidine breaks down and incorporates into cytoplasmic macromolecules, not DNA, suggesting caution in its use.
6 citations
,
November 2010 in “Histochemistry and cell biology” This study found that transthyretin and megalin expression in human scalp hair follicles varies significantly with the hair growth cycle, peaking during anagen and diminishing in catagen and telogen phases.
47 citations
,
July 1997 in “British Journal of Dermatology” This research observed that during the catagen phase, the inner root sheath of hair follicles becomes an early target, highlighting its potential role in maintaining hair follicle homeostasis.
8 citations
,
February 2017 in “Archives of Dermatological Research” This study found that IPL hair reduction led to significant decreases in hair count and thickness by promoting hair follicle miniaturization, increased telogen phase, and reduced cell proliferation.
This study found that hair germ and epidermal basal cells differ in keratin expressions in rat hair tissues, with hair-specific keratins appearing after the differentiation of each layer.
35 citations
,
March 2010 in “British journal of dermatology/British journal of dermatology, Supplement” This study demonstrates that mouse eyelashes can effectively model human eyelash growth to analyze morphology, development, and the effects of growth-stimulatory agents like bimatoprost.
1 citations
,
January 2007 in “AIP conference proceedings” This study used phase contrast hard x-ray microscopy to capture detailed images of healthy human hair, revealing distinct structures such as the medulla, cortex, and cuticular layer.
This study successfully established a functionally stable immortalized sheep granulosa cell line (GCs-SV40T-GFP) that can passaged up to 50 generations, maintaining morphological stability and estradiol secretion, offering a valuable model for research into animal reproductive function and hormone regulation.
October 2019 in “Skin appendage disorders” This study revisits and reproduces Felix Pinkus' concept of the vitreous membrane in hair follicles, suggesting these structures may play a role in differentiation or nutrition due to their location in metabolically dynamic regions.
May 2012 in “International Journal of Dermatology and Venereology” This article reviews the morphogenesis and cycling of hair follicles and the complex signaling pathways involved, without reporting new experimental results.
January 2015 in “Chinese Veterinary Science” This study observed distinct changes in the ultrastructure of Hexi cashmere goat hair follicles throughout the year, highlighting stages with specific cellular and structural characteristics.
9 citations
,
June 2014 in “British Journal of Dermatology” The study found that balding scalps have more thin hairs and larger oil glands, which might contribute to skin conditions related to hair loss.
June 2026 in “Reports of Morphology” This study on female Wistar rats with stress-induced alopecia found that a modified diet rich in antioxidants and nutrients reduced dystrophic skin changes and preserved the functional activity of hair follicles, suggesting dietary approaches may support hair restoration under chronic stress conditions.