research Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage: An Experimental Animal Study
Finasteride may cause kidney damage.
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research Cutaneous Manifestations of Systemic Infection in Children
Skin symptoms are important for diagnosing infections in children.
research Recent Updates of the CRISPR/Cas9 Genome Editing System: Novel Approaches to Regulate Its Spatiotemporal Control by Genetic and Physicochemical Strategies
CRISPR/Cas9 has improved precision and control but still faces clinical challenges.
research Age-Related Macular Degeneration in Patients with Androgenetic Alopecia: Could the Monocyte/HDL Ratio Be the Link?
Hair loss might be linked to eye aging due to inflammation markers in blood.
research Effects of Calcitriol Combined with Metformin in the Treatment of Polycystic Ovary Syndrome and Its Influence on Serum Monocyte Chemotactic Factor-1
Calcitriol and metformin together are more effective for treating PCOS and lowering MCP-1 than metformin alone.
research Cardiac and Brainstem Neuroinflammatory Pathways Account for Androgenic Incitement of Cardiovascular and Autonomic Manifestations in Endotoxic Male Rats
Testosterone plays a big role in heart and nervous system damage caused by inflammation in male rats, suggesting that blocking testosterone production could help manage this condition.
research Neutralizing Alpha-Toxin Accelerates Healing of Staphylococcus Aureus-Infected Wounds in Normal and Diabetic Mice
Blocking α-toxin helps heal Staphylococcus aureus-infected wounds faster in both normal and diabetic mice, with different effects on their immune responses.
research Toxicological Study on the Health Effects of Long-Term Exposure to Benzene in Benzene Filling Workers, Qassim Region, KSA
Long-term exposure to benzene increases skin diseases, blood disorders, and liver problems.
research Finasteride Delays Atherosclerosis Progression and Reduces Hepatic Inflammation in Low-Density Lipoprotein Receptor-Deficient Mice
Finasteride may slow down heart disease by lowering cholesterol and reducing inflammation.
research Pro-Inflammatory Cytokine Cascade in Human Plucked Hair
Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.
research Dermatologic Manifestations of Human Immunodeficiency Virus Infection
HIV can cause unusual and severe skin problems that are hard to treat.
research Oral Manifestations of Hematologic and Nutritional Diseases
Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.
research Skin Manifestations Among GATA2-Deficient Patients
Patients with GATA2 deficiency show early skin symptoms that help diagnose the condition.
research High-Dose Pulsed Corticosteroid Therapy Combined with Methotrexate for Severe Alopecia Areata in Childhood
High-dose corticosteroids and methotrexate had a modest effect on severe childhood alopecia, but side effects and relapse were concerns.
research CD99 Is Strongly Expressed in Basal Cells of the Normal Adult Epidermis and Some Subpopulations of Appendages: Comparison with Developing Fetal Skin
CD99 is highly present in certain skin cells and could help treat skin conditions.
research Minimum Requirements for Reporting Clinical Trials Evaluating the Therapeutic Potential of Platelet-Rich Plasma
The document sets guidelines to standardize reporting of PRP clinical trials for better reproducibility and comparability.
research Beneficial Effects of Finasteride on Hepatic and Pulmonary Immune Response After Trauma Hemorrhage in Mice
Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.
research Risk of Periodontal Diseases in Women With Polycystic Ovary Syndrome: An Overview
Women with PCOS are at higher risk for gum disease, and managing shared risk factors can help both conditions.
research Effect of Gingivitis on Anti-Mullerian Hormone in Females with Polycystic Ovary Syndrome
Gingivitis may increase a hormone linked to ovarian function in women with a certain ovary condition, and treating gum disease could help manage it.
research Acute Disseminated Paracoccidioidomycosis with Molluscoid Lesions in a Young Woman
A young woman with a rare fungal infection showed significant improvement after treatment with antifungal medication.
research Keratins in Health and Cancer: More Than Mere Epithelial Cell Markers
Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
research Complications of Cushing's Syndrome: State of the Art
Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research Multiple Sclerosis: Side Effects of Interferon Beta Therapy and Their Management
The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.
research Severe Cutaneous Adverse Reactions to Drugs
Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.
research Timing of Expression of the Core Clock Gene Bmal1 Influences Its Effects on Aging and Survival
The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
research On the Role of Melatonin in Skin Physiology and Pathology
Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
research Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails
Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.
research Epigenetic Control of Adult Stem Cell Function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research Cutaneous Lupus Erythematosus: A Review
Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.