research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
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research Protective Effects of Finasteride on the Pulmonary Immune Response in a Combined Model of Trauma-Hemorrhage and Polymicrobial Sepsis in Mice
Finasteride helps reduce lung inflammation and damage after trauma and infection.
research Plumbagin, A Natural Compound With Several Biological Effects And Anti-Inflammatory Properties
Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.
research Pharmacologic Interventions in Aging Hair
Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
research Pro-Inflammatory Cytokine Cascade in Human Plucked Hair
Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.
research Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome
Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
research Treatment-Refractory Central Centrifugal Cicatricial Alopecia Responsive to a Novel Botanical Treatment
A new plant-based treatment was effective for hair regrowth in women with a specific type of hair loss that didn't respond to usual treatments.
research Editors' Picks
ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.
research Risk of Periodontal Diseases in Women With Polycystic Ovary Syndrome: An Overview
Women with PCOS are at higher risk for gum disease, and managing shared risk factors can help both conditions.
research Recent Understandings of Biology, Prophylaxis, and Treatment Strategies for Hypertrophic Scars and Keloids
The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
research Evaluation of a Novel Dry Eye Model Induced by Oral Administration of Finasteride
Finasteride causes reduced tear flow and severe eye inflammation.
research Lichen Planopilaris Responsive to a Novel Phytoactive Botanical Treatment: A Case Series
A new botanical treatment improved hair growth and symptoms in lichen planopilaris patients.
research 5-Bromo-2′-Deoxyuridine Induced Effluvium via p53-Mediated CD326-Positive Keratinocyte Apoptosis in C57BL/6 Mice
A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.
research Is Androgenetic Alopecia a Photoaggravated Dermatosis?
Sunlight worsens hair loss; protect scalp.
research The Circadian Clock in Skin
The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
research Perilla Frutescens: A Rich Source of Pharmacologically Active Compounds
Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.
research Therapeutic Anti-Inflammatory Potential of Formyl-Peptide Receptor Agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research A Role of Placental Growth Factor in Hair Growth
Placental growth factor may help treat hair loss.
research The Therapeutic Potential of CRTH2/DP2 Beyond Allergy and Asthma
CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.
research Skin Wound Healing in Humans and Mice: Challenges in Translational Research
The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
research Interrelation of Immunity and Tissue Repair or Regeneration
The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches
Fat cells are important for tissue repair and stem cell support in various body parts.
research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Wound Healing
Wound healing is complex and requires more research to enhance treatment methods.
research Chemokine C-C Motif Ligand 7 (CCL7), a Biomarker of Atherosclerosis, Is Associated with the Severity of Alopecia Areata: A Preliminary Study
Higher levels of CCL7 are linked to more severe hair loss in alopecia areata patients.
research The Endocannabinoid System of the Skin: A Potential Approach for the Treatment of Skin Disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research The Profibrogenic Role of Neutrophil Extracellular Traps in Stenotic Crohn's Disease: A New Antifibrotic Target?
Targeting NETs may help reduce fibrosis in Crohn's disease.
research Innate Immunity and the Regulation and Mobilization of Keratinocyte Stem Cells: Are the Old Players Playing a New Game?
Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.