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This study explored the use of dexamethasone-loaded polymer hybrid nanoparticles in a xanthan gum hydrogel for treating alopecia areata, finding that freeze drying with sucrose influenced particle size, release, and permeation, but had no impact on cytotoxicity or anti-inflammatory efficacy in human keratinocytes.

This study suggests that Vigilon®, a new occlusive wound dressing with high water content, may promote better wound healing than other similar dressings in dermatologic surgery.

This study concluded that polymeric nanoparticles effectively targeted hair follicles for drug delivery, but the organogel formulation did not enhance their penetration into the hair shaft.

This study found that polycaprolactone (PCL) in facial fillers led to more cell proliferation and vascular activity than hyaluronic acid (HA) in Wistar rats, suggesting enhanced tissue regeneration effects with PCL.

In this study, a novel nanocomposite hydrogel was developed for diabetic wound care, demonstrating superior tissue adhesion, antibacterial properties, and healing capabilities in vivo and in vitro, while also allowing real-time pH monitoring to aid clinical management.

This review reports that cubosomes, used as drug nanocarriers in topical treatments, offer potential benefits for managing skin and eye diseases by improving bioadhesion, retention, and sustained release compared to conventional formulations, but also face manufacturing and biological challenges for effective clinical outcomes.

In this study, researchers developed a novel composite fiber by incorporating minoxidil sulfate-loaded ZIF-8 nanoparticles into a polyvinyl alcohol matrix, achieving sustained drug release for up to 220 hours, strong mechanical properties, and the capability for cosmetic applications like wigs.

This review discusses the medical and dental applications of polyhydroxyalkanoates (PHAs), highlighting their potential for improving drug delivery and providing biocompatible solutions for medical devices, but reports no new clinical results.

This study observed that dermal papilla cell aggregates showed increased viability and gene expression on softer 3D substrates, indicating the importance of substrate stiffness in cellular behavior.

This study found that MPEG-dihexPLA micelles significantly improved the skin deposition of tacrolimus compared to a marketed ointment, suggesting better targeted delivery with reduced systemic absorption.

Hair fibers may have a unique, non-protein sheath not previously identified.

This study found that applying Laponite clay gels to skin wounds in mice did not speed up wound closure but significantly improved healing quality compared to phosphate-buffered saline or alginate treatments, with benefits such as enhanced re-epithelialization and hair follicle stimulation near wounds.

In their 1957 study, Neuman and Neuman suggested that magnesium deficiency may inhibit the ion exchange process required for calcium ions to enter extracellular fluid, potentially affecting calcium mobilization.

This study found that a novel hybrid bilayer scaffold system enhanced wound healing in an in-vivo model by promoting cell viability, migration, and preventing infection, showing potential as an advanced dressing for cutaneous wounds.

In this study, a hydrogel with anti-inflammatory, antibacterial, antioxidant, and wound tissue adhesion properties was developed, showing significant potential for wound healing and suggesting it could offer a new and effective treatment option in clinical settings.

This case report suggests that crisaborole may be an effective alternative treatment for alopecia areata in pediatric patients, showing significant hair regrowth after two weeks in a 10-year-old girl.

This study found that chemically modifying human hair through esterification or disulfide reduction and alkylation affects the hair's viscoelastic properties, including stability, integrity, and response to moisture.

This review examined natural hair gels, incorporating an experimental polyherbal gel, and reported that these formulations possess multifunctional benefits for hair health, while also highlighting the importance of product safety and potential for innovative delivery systems.

The researchers reported that increasing protein content in human hair keratin/calcium alginate blend films led to larger molecular aggregates, which influenced the films' physical properties such as light transmittance and tensile strength.

This study reports that novel core-ABS nanocarriers efficiently loaded with dexamethasone and finasteride show potential for dermal drug delivery, exhibiting non-toxic interactions with human keratinocyte cells and skin penetration.

This study proposed the existence of a membrane-like structure between the cuticle and cortex in human hair, which may provide strong protection against external stimuli.

This research evaluated the wound healing potential of NIMO-CH, a cellulose hydrogel with indigenous microorganisms, in ICR mice and found complete wound closure with hair growth by day 18-20, suggesting it could be a viable alternative for wound care.

This study found that a novel hydrogel scaffold, cGEL, significantly increased melanin production and melanotic gene expression in human melanocytes compared to other graft materials, suggesting its potential as a superior carrier for skin grafting.

This study found that formulation factors like pH, viscosity, and chemical enhancers can significantly influence intrafollicular hydrocortisone permeation in vitro, with higher pH and enhancers reducing follicular contribution.

This structural study reports on the crystal properties of a compound used for treating alopecia, revealing different conformations and nitrogen hybridization in its piperidine rings.

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