10 citations
,
January 2007 in “Dermatologic Surgery” The study reported that using polyamide hair fiber implants may be an effective adjunctive treatment for scalp scars, with most patients experiencing no complications.
6 citations
,
January 1989 In this study, synthetic hair implantation for small bald areas in patients with cicatricial or androgenetic alopecia showed varied results in hair density, durability, and complications over six months.
January 2007 in “Dermatologic Surgery” This study found that implanting polyamide hair fibers may serve as a supplementary treatment for scalp scars, with most cases showing favorable outcomes and manageable complications.
3 citations
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June 2019 in “Dermatologic Therapy” This study reported that the Biofibre® hair implantation system, used on 1,518 patients with various degrees of baldness and causes of alopecia, delivered immediate and visible results without scarring or hospitalization, which greatly improved patients' self-esteem and psychological well-being.
18 citations
,
January 2000 in “Journal of Adhesion Science and Technology” This research found that immobilizing type I atelocollagen onto artificial hair significantly improved the adhesion and long-term fixation of the hairs in the human scalp, indicating high biosafety and enhanced tissue integration.
4 citations
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February 2020 in “Journal of Cosmetic Dermatology” This study reported significant moderate-to-severe complications in two patients following synthetic hair fiber implantation, including recurrent infections, scalp issues, and granulomatous reactions, which were only resolved once the fibers were removed despite initial treatment attempts with antibiotics.
1 citations
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April 2022 in “Journal of Biological Regulators and Homeostatic Agents/Journal of Biological Regulators & Homeostatic Agents” This study reported that among 1337 patients receiving biocompatible artificial hair implants, common side effects included mild inflammation (7%) and itching (<3%), while patient satisfaction was high at 96%, though COVID-19 may have impacted some results.
January 2018 in “Archives of general internal medicine” The document concludes that automatic biofiber hair implant is a new method for improving hair growth.
This study found that an injectable hair material showed good biocompatibility in micropigs and effectively promoted dermal thickening, suggesting its potential as a new soft tissue filler.
4 citations
,
June 1983 in “The Journal of dermatologic surgery and oncology” This paper discusses therapies for damaged scalps from hair and fiber implants and reports no new clinical findings, calling attention to treatment complexities.
8 citations
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June 1979 in “JAMA” This article discussed the ineffectiveness and dangers of implanting synthetic hair fibers for pattern baldness, noting they can cause severe infections, yet such clinics remain operational.
22 citations
,
May 2004 in “Tissue Engineering” This study found that collagen sponges with polyglycolic acid fibers support proper skin and hair follicle restructuring, suggesting potential usefulness for hair reconstitution research and clinical applications.
15 citations
,
January 1992 in “Dermatology” This study found severe cutaneous complications after artificial hair implantation were associated with acute inflammatory and granulomatous infiltrates, suggesting bacterial infections significantly contribute to these complications.
January 2025 in “SSRN Electronic Journal” January 2008 in “Chinese Journal of Aesthetic and Plastic Surgery” This study found that an injectable material derived from hair shows good biocompatibility and promotes dermal thickness in pigs, suggesting potential as a new soft tissue filling agent.
2 citations
,
May 2016 in “Hair transplant forum international” This article discusses the limitations in the design or mechanism of hair implanter pens and reports no new findings.
2 citations
,
June 1979 in “JAMA” This article reviews the ineffectiveness and potential dangers of synthetic fiber implantation for pattern baldness and reports no resolution of their ongoing use despite safety concerns.
1 citations
,
February 2017 in “Dermatologic Surgery” This study observed that using a basement membrane matrix significantly improved hair follicle reconstruction in a mouse model, leading to quicker hair formation and a greater number of hair shafts compared to a control medium.
1 citations
,
July 2023 in “International Journal of Biological Macromolecules” In this study, researchers developed a composite paste system using minoxidil-loaded nanoparticles and valproic acid, enhanced by roller-microneedles, which significantly stimulated hair regeneration and perifollicular vascularization in an androgenetic alopecia mouse model, reducing side effects compared to traditional treatments.
May 2026 in “International Journal of Biological Macromolecules”
7 citations
,
May 2011 in “Hair transplant forum international” This report presents no new clinical results; it discusses the application of ACell MatriStem™, a porcine urinary bladder-derived extracellular matrix, in wound healing.
4 citations
,
October 2019 in “Journal of Dermatological Treatment” This study reported that injecting monofilament threads into the scalp significantly improved hair count and hair mass index in women with female pattern hair loss, with most participants noticing substantial improvements in hair characteristics compared to a placebo.
1 citations
,
May 2022 in “International journal of trichology” This study found that using a keratin hair fiber filler significantly improved patient satisfaction, hair volume perception, and confidence among alopecia patients, without serious adverse effects.
October 2022 in “Regenerative Biomaterials” This study demonstrated that fibrin hydrogels support skin-derived precursors in hair follicle neogenesis in mice, with new hair growth and regeneration of blood vessels and sebaceous glands observed.
February 2024 in “International Journal of Biological Macromolecules” In this study, researchers developed a microfluidic-assisted technology to create dual-layer microspheres containing mesenchymal and epidermal cells, which efficiently induced hair follicle regeneration in mice, suggesting potential improvements for hair regeneration treatments in conditions like androgenetic alopecia.
September 2021 in “Hair transplant forum international” This case report documents severe scalp necrosis and permanent scarring in a man following synthetic hair implantation, which was performed without sufficient risk disclosure.
1 citations
,
December 2017 in “JAMA Facial Plastic Surgery” This study found that both PHDPE and ePTFE hair-bearing scaffolds were well tolerated in a rat model, with minimal infection or extrusion, though artificial hair showed progressive loss over time.
28 citations
,
December 2016 in “Journal of Biomedical Materials Research Part A” This study found that mesenchymal progenitor cells from human hair roots seeded onto polymer scaffolds stimulated the production of mineralized proteins, enhancing bone-like structures, with optimal results at a pore size of 35 µm.
1 citations
,
January 2017 in “PubMed” This study found that despite chemical differences, five different brands of reconstructive hair fibers all provided successful cosmetic results in disguising hair loss in patients.
July 2026 in “Bioactive Materials” This study demonstrated that degradable core-shell cryomicroneedles loaded with hair follicle organoids supported natural-like hair regeneration in mice, offering a promising approach for controllable follicular unit regeneration in baldness.