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Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Noggin is necessary to start the hair growth phase in skin after birth.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Stem cell niches support, regulate, and coordinate stem cell functions.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Androgens can cause hair growth in some areas and hair loss on the scalp.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.

Stem cells from hair follicles can safely treat hair loss.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.

Hair grays due to oxidative stress and fewer functioning melanocytes.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.