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This article reviews the therapeutic use of carnitine derivatives for re-establishing mitochondrial functionality in aging and reports no new clinical results.

This review highlights morphological factors contributing to age-related alopecia and suggests further research to understand and potentially mitigate cellular aging processes affecting hair quality.

This research observed that chronological age, rather than hearing loss, primarily affects the auditory cortex in aging, and found that brain aging in PolG mice mirrored that of wild-type counterparts, suggesting differential tissue sensitivity to mitochondrial dysfunction.

The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.

This study found that transient mtDNA double strand breaks in mice accelerated aging in certain tissues through increased reactive oxygen species, independent of p21/p53 pathway mediation.

This source critically examines Bruce Ames's influential contributions to biochemistry, particularly his theories on oxidative stress and mitochondrial DNA damage in aging, while acknowledging current challenges to his work and highlighting his lasting impact on the fields of mutagen screening and public health.

This review discusses age-related changes in scalp skin and their potential effects on hair follicle aging, but reports no new clinical results, calling for further investigation.

This review summarizes current literature associating mitochondrial dysfunction with dermatologic issues like skin aging, hair loss, and poor wound healing, noting potential benefits in targeting mitochondrial components for treatments.

This review discusses the hyperfunction theory of aging as a key factor in COVID-19 vulnerability, highlighting the potential of anti-aging interventions like rapamycin to reduce this risk.

This ex vivo study reported that melatonin significantly improved certain aging biomarkers in aged human skin, including reduced mTORC1 activity, increased fibrillin-1, and enhanced collagen and elastic fiber organization, though other key biomarkers remained unchanged.

This review discusses the impact of melatonin and its metabolites on skin aging, summarizing how they may serve as "aging neutralizers" through their anti-oxidative and anti-inflammatory properties, but reports no new clinical results.

This study provides a comprehensive overview of human umbilical cord mesenchymal stem cell-derived extracellular vesicles (HUCMSC-EVs), suggesting their potential to combat aging and alleviate age-related disorders by rejuvenating multiple organs in animal models and discussing engineering strategies to harness their full anti-aging potential.

This study found that oxidative damage is present in the mitochondria of PolG mice, which exhibit premature aging-like phenotypes due to mitochondrial dysfunction.

This study found that treating mtDNA mutator mice with the antioxidant SkQ1 delayed aging traits and extended their lifespan, potentially by alleviating mitochondrial dysfunction caused by reactive oxygen species.

This review discusses the potential dermatological applications of Dendrobium officinale polysaccharides, noting their hair growth promoting, skin moisturizing, and antioxidant effects, but reports no new clinical results.

This study found that the PPAR-γ modulator N-acetyl-GED may enhance mitochondrial function in human hair follicles, particularly in outer root sheath keratinocytes.

This review examines melatonin's potential effects on human skin and hair follicle pigmentation, highlighting the need to confirm findings from cell cultures in physiological tissue contexts.

This review discusses the role of mineral nutrients in human health, emphasizing the importance of dietary sources and education to prevent mineral deficiencies, and reports no new clinical results.

This article highlights advances in various physiological studies, including vitamin E's potential to improve aging-related outcomes in mice, but does not present new experimental results.

This review highlights the potential of transcranial photobiomodulation (tPBM) as a non-invasive and affordable treatment for brain diseases, summarizing recent advances and successful protocols based on over two decades of research.

This study used computational modeling to identify key genes and miRs involved in cardiac aging, finding a strong relationship supported by literature and some experimental validation in aged mouse hearts.

This review discusses the potential role of oxidative stress in hair graying and age-related alopecia, emphasizing the need for new strategies to counteract these effects, but reports no new results.

This study found that loading CoQ10 into a protransfersomal emulgel improved its stability and anti-ageing effects in UV radiation skin-aged induced-mice, without causing skin irritation.

This review discusses factors affecting hair aging, such as inflammation and UV exposure, and examines potential anti-aging benefits of antioxidants and nutraceuticals for hair, but reports no new clinical results.

This review discusses the use of nutraceuticals in dermatology for preventing and reversing signs of skin aging, but it reports no new clinical results.

This article reviews age-related changes in facial structure at a cellular level and summarizes potential solutions for rejuvenation surgery, but reports no new clinical results.

This computational study developed a regulatory model linking key genes and miRNAs to cardiac senescence, validated by connecting 94% of these elements to existing cardiac aging research.

This study found that Dendrobium sabin flower extracts, especially the methanolic one, demonstrated strong antioxidant and anti-aging properties without significant toxicity, suggesting its potential in treating photo-induced skin aging.

This study found that Si Jun Zi Tang may have anti-aging effects in mice, linked to inhibition of the PI3K-AKT and P38 MAPK signaling pathways.

This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.