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This study identified specific miRNAs associated with hair follicle development in chicken embryos, highlighting miR-1623's involvement in regulating WNT4 and contributing to hair follicle cell growth.

This study reveals that the microRNA-200 family, highly enriched in hair matrix progenitors, restricts sebaceous gland development by inhibiting the SOX9-dependent lipogenic program, highlighting its specific role in epithelial plasticity within hair follicles.

This editorial synthesizes research on UV-induced skin damage, highlighting potential therapeutic strategies by mapping cellular changes, identifying molecular mechanisms, demonstrating melanocyte protection, and proving combination therapy effectiveness in conditions like vitiligo.

In this study, miR-181a was found to inhibit the proliferation and induction abilities of ovine dermal papilla cells by targeting the GNAI2 gene and affecting the Wnt/β-Catenin signaling pathway, highlighting its role in the regulation of hair follicle growth and development.

This review outlines that in women with PCOS, microRNAs (miRNAs) are abnormally expressed in various tissues compared to those without the condition, suggesting these miRNAs as potential biomarkers and therapeutic targets, given their role in pathways critical to PCOS and potential interactions affecting reproductive outcomes.

This study found that treating cashmere goat kids with melatonin significantly increased secondary hair follicle density, improving cashmere quality and yield, likely through mechanisms involving the MAPK signaling pathway.

In this study, researchers identified known and novel miRNAs in Liaoning Cashmere goat skin and found differences in miRNA expression linked to cashmere fineness, providing new insights into LCG goat skin biology.

This computational study developed a regulatory model linking key genes and miRNAs to cardiac senescence, validated by connecting 94% of these elements to existing cardiac aging research.

This article reviews the multifaceted roles of adipose tissue in skin biology and highlights its potential implications for epidermal homeostasis and wound healing; it reports no new research findings.

In this integrative study, the researchers examined microRNA-mRNA networks related to androgenetic alopecia and found that miR-146b-5p may promote hair growth and improve inflammation, highlighting a potential therapeutic target for the condition.

This study found that low-passage exosomes from dermal papilla cells enhance hair follicle stem cell proliferation and that miR-218-5p may serve as a potential biomarker and therapeutic target for hair growth.

This study investigated bovine milk-derived exosomes and found they significantly increased dermal papilla cell viability and up-regulated WNT pathway components in human hair follicles, suggesting potential therapeutic value for hair loss disorders like androgenetic alopecia and telogen effluvium.

The researchers developed a comprehensive human skin cell atlas using data from various studies and established a consensus nomenclature for normal human skin in this project, which also includes a deep learning-based method for more effective reference mapping of new cells.

In this study, researchers found that the microRNA profiles of induced pluripotent stem cells (iPSCs) derived from different adult cell types are largely similar, although each line exhibits some unique gene expression, distinct from both their cells of origin and embryonic stem cells.

This study found that exosomes from human umbilical cord mesenchymal stem cells significantly promoted hair follicle growth and enhanced the transition to the growth phase in a model of androgenetic alopecia, by enriching specific microRNAs that activate key pathways involved in hair regeneration.

This study observed distinct plasma miRNA profiles in alopecia areata, identifying several miRNAs downregulated in both mild and severe forms; machine learning models demonstrated strong predictive accuracy, and kinase inhibitors were suggested as promising therapeutic targets based on pathway analysis.

In this study, researchers found that Fgf21 knockout mice exhibited delayed hair follicle cycling compared to wild-type mice, potentially due to altered miRNA interactions affecting Vezf1 and Map3k1 expression, providing insights into the molecular regulation of hair growth.

This study found that in Liaoning cashmere goats, overexpression of the PIP5K1A gene enhances skin fibroblast proliferation, while interference with this gene reverses melatonin-induced proliferation, and PIP5K1A regulates certain miRNA expressions, suggesting a role in improving cashmere yield and quality.

This study found that hypoxia-preconditioned HF-MSC-derived exosomes improved therapeutic outcomes in models of ulcerative colitis, potentially through miR-214-3p-mediated pathways affecting mitochondrial function and inflammatory responses.

This research suggests that recent discoveries of signaling pathways in androgenic alopecia may pave the way for targeted therapies, providing potential new treatment options beyond the current FDA-approved drugs, minoxidil and finasteride.

This study found that TLR3 activation in human keratinocytes enhances exosome biosynthesis and expression of hair follicle stem cell markers, suggesting a potential mechanism for tissue regeneration.

This study suggests that early-stage dermal papilla cell-derived exosomes may enhance adipose stem cells' hair inductive abilities through specific miRNAs.

This study found that overexpression of miR-1246 in peripheral CD4+ T cells can reduce markers associated with inflammation and T cell activation in severe active alopecia areata, suggesting potential therapeutic benefits.

This study found that inducing miR-205 reduces actin contractility and stiffness in hair follicle stem cells and progenitors, stimulating hair regeneration in both young and old mice.

This study demonstrates that Sox11 and Sox4 are crucial for activating embryonic-like programs during wound healing, with Sox11 overexpression impairing skin differentiation and promoting genes linked to embryonic epidermis.

In this study, researchers found that patients with alopecia areata had significantly higher levels of miR-203 in their skin compared to healthy controls.

This review discusses the role of microRNA in skin development and disease, highlighting its potential for novel therapies, and reports no clinical results.

This study found that miR-486 and miR-451 levels were reduced in alopecia areata-affected skin, and delivering their mimics to mice mitigated symptoms by reducing inflammation and immune activity.

This study found that dysregulated microRNA expression in mice may be linked to aberrant gene activity that contributes to the development of alopecia areata.

This study explored the role of nine specific miRNAs in human hair follicles, revealing significant miRNA/mRNA correlations for miR-24, miR-31, and miR-106a and identifying target genes involved in hair biology.