18 citations
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January 2006 in “Analytical Sciences” This study found that the FIA-amperometric method for minoxidil quantification in pharmaceutical preparations provided accurate results comparable to the conventional UV technique, indicating no systematic errors.
13 citations
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September 2005 in “Eclética Química” This study found that a photometric flow titration using KMnO4 and minoxidil provided results comparable to a chromatographic procedure, with recoveries between 97.6% and 102.8% and relative errors of 3.5% to 4.0%.
4 citations
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January 2009 in “Eclética Química” This study described a potentiometric titration method for determining minoxidil, which showed recoveries of 97.4 to 98.7% and agreed with chromatographic results within a 90% confidence level.
November 2009 in “Eclética Química” In this study, a potentiometric titration method was developed for determining minoxidil, achieving recoveries of 97.4% to 98.7%, and it showed agreement with a chromatographic procedure at a 90% confidence level.
20 citations
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October 2004 in “Journal of Pharmaceutical and Biomedical Analysis” Quick method to measure minoxidil in blood, accurate and useful for labs.
4 citations
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May 2020 in “Medicine in Drug Discovery” This study found that arylsulfatase enzymes in hair follicles can convert the active form of minoxidil back to its inactive form, potentially affecting its effectiveness in treating androgenetic alopecia.
September 2005 in “Eclética Química” This study demonstrated that a photometric flow titration method using KMnO4 and minoxidil provided recovery rates of 97.6 to 102.8% for commercial samples, with relative errors of 3.5 to 4.0% compared to chromatographic procedures.
March 2025 in “Analytical Methods in Environmental Chemistry Journal” This study developed a spectrophotometric method to determine minoxidil in pharmaceuticals, creating a highly sensitive, simple, and cost-effective approach using a synthesized charge transfer complex with a notable absorption peak at 505 nm.
May 2019 in “International Journal of Research In Pharmaceutical Chemistry and Analysis” This study developed and validated a UV spectrophotometric method for accurately estimating Minoxidil in tablet form, showing linearity across concentrations from 1-6µg/ml.
4 citations
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January 2011 in “Analytical Letters” This study demonstrated that a flow injection method using potassium permanganate for detecting minoxidil provided accurate recoveries and agreed closely with HPLC results, showing potential for effective analysis of commercial samples.
January 2011 in “Journal of Jiangnan University” This study developed a validated method for analyzing minoxidil in hair care cosmetics, demonstrating good precision and recovery rates.
12 citations
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September 2021 in “Journal of molecular structure” In this study, researchers created a new molecular salt from minoxidil and 2,4-dihydroxybenzoic acid, finding it superior to raw minoxidil for promoting hair growth in a mouse model, suggesting it may be a promising candidate for treating hair loss.
January 2014 in “Food and Drug” This study established an accurate, reliable, and sensitive HPLC method to detect the illegal addition of minoxidil in herbal hair growth products.
May 2024 in “Research Journal of Pharmacy and Technology” This study introduced new spectrophotometric methods to estimate Minoxidil in pharmaceutical forms, demonstrating its linearity across various buffers and solvents, and found these methods to be simple, economical, and effective according to ICH guidelines.
8 citations
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January 2011 in “Collection of Czechoslovak Chemical Communications” This study developed and validated a sensitive method using adsorptive cathodic stripping voltammetry to directly determine minoxidil in topical solutions, shampoos, and creams, achieving high recovery rates and precision.
6 citations
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July 2005 in “Farmaco” This study developed a micellar electrokinetic capillary chromatography method for determining minoxidil in Rogaine and generic products, offering a simple and efficient alternative to HPLC.
June 2025 in “Indian Journal of Heterocyclic Chemistry” In this study, researchers developed a precise and rapid method for simultaneously analyzing minoxidil and finasteride in local therapeutic formulations, ensuring that the excipients did not interfere, making it suitable for routine quality control.
25 citations
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January 1983 in “Analyst” Method measures minoxidil in tablets accurately and easily.
19 citations
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September 1999 in “Talanta” New method measures minoxidil concentration faster, more accurately, and automatically.
June 2025 in “Samarra Journal of Pure and Applied Science” This study developed a rapid and accurate spectrophotometric method using diazotized sulfanilic acid to measure minoxidil in both pharmaceutical formulations and pure form, demonstrating high precision and linearity within a concentration range of 5-40 μg/ml.
14 citations
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May 2005 in “Farmaco” This study developed a high performance capillary electrophoresis method, validated for both legal and illicit minoxidil-based products, to confirm minoxidil's presence alongside known impurities.
9 citations
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May 2020 in “Journal of Pharmaceutical and Biomedical Analysis” This study developed an efficient LC-MS bioanalytical method to simultaneously quantify minoxidil sulphate and latanoprost in skin layers, supporting the formulation of topical treatments for androgenic alopecia.
January 2016 in “Huanjing yu Jiankang Zazhi”
This study validated an HPLC-UV method to detect minoxidil in cosmetic products and found that 2 out of 9 analyzed products contained minoxidil, despite international regulations banning its inclusion due to potential systemic absorption.
January 2025 in “Revista Vitae” In this study, researchers found that 2 out of 9 analyzed cosmetic hair growth products contained the banned substance minoxidil, demonstrating the presence of this antihypertensive drug in some cosmetics despite regulations.
13 citations
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April 2013 in “Chinese Chemical Letters/Chinese chemical letters” This study developed and validated a sensitive HPLC–MS/MS method for detecting seven prohibited substances in cosmetic products.
January 2019 in “Analytical Science and Technology” This study developed a rapid method using advanced chromatography and mass spectrometry to detect hair-growth enhancing compounds, discovering synthetic drugs in about 21% of tested supplements.
2 citations
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November 2017 in “Food Additives & Contaminants: Part A” This study developed a validated method to detect prohibited drugs in dietary supplements, finding minoxidil, triaminodil, and finasteride in some samples.
June 2023 in “Journal of chemical metrology” This study used LC-HRMS to detect undeclared pharmaceutical ingredients like minoxidil and finasteride in hair serums, finding risk to public health due to their toxicological properties and advocating for manufacturer transparency.
This study found that an herbal extract from Marking nuts, when compared to a standard drug, effectively inhibited the dandruff-causing organism Malassezia furfur and promoted hair growth on mice, suggesting potential use for dandruff treatment and hair rejuvenation.