TLDR Scientists developed a cheaper, but slower, method to measure minoxidil in hair loss treatments with high accuracy.
In 2009, researchers developed a potentiometric titration method to measure minoxidil in commercial topical pharmaceuticals, using a redox reaction with potassium dichromate in sulfuric acid at 60°C. The method, which had minoxidil and potassium dichromate concentrations of 1.00 x 10^-2 mol L^-1 and 1.00 x 10^-3 mol L^-1 respectively, was applied to Regaine® and Neoxidil samples, yielding recoveries between 97.4% and 98.7%. The results were comparable to chromatographic methods within a 90% confidence level, suggesting this approach as a cost-effective, albeit time-consuming, quality control option for pharmacies.
13 citations,
September 2005 in “Eclética Química” Quick, accurate minoxidil measurement in hair loss products using photometric flow titration.
19 citations,
September 1999 in “Talanta” New method measures minoxidil concentration faster, more accurately, and automatically.
25 citations,
January 1983 in “Analyst” Method measures minoxidil in tablets accurately and easily.
4 citations,
January 2011 in “Analytical Letters” The method quickly and accurately measures minoxidil in drugs, comparable to standard techniques.
1 citations,
January 2022 in “Brazilian Journal of Pharmaceutical Sciences” Minoxidil can be effectively encapsulated in coated nanovesicles for potential drug delivery.
52 citations,
February 2014 in “European Journal of Pharmaceutical Sciences” Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.
2 citations,
January 2018 in “Biomolecules & therapeutics” Polyamidoamine dendrimers can change the strength and direction of electroosmotic flow through the skin, affecting drug delivery.
November 2009 in “Eclética Química” The conclusion cannot be provided as the document content is not available.
