This review examines current treatment options for alopecia areata and highlights the challenges due to limited evidence-based data and unpredictability in disease progression.
June 2008 in “British Journal of Dermatology” Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.
July 1996 in “College & Research Libraries News” This paper reviews the causes, treatments, and cultural attitudes towards male pattern baldness but presents no new research findings.
7 citations
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January 2018 in “Skin appendage disorders” This article reviews the historical development of trichology and proposes the term "trichiatrist" for physicians specializing in the medical treatment of hair and scalp, noting no new clinical findings.
66 citations
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December 2014 in “Nature Communications” Fibroblasts can be turned into melanocytes for potential skin treatments.
2 citations
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December 2024 in “Environmental Science and Pollution Research” 1 citations
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April 2023 in “Animals” In this study, Min pigs were found to have unique characteristics for secondary hair growth compared to Berkshire and Yorkshire pigs, with the Wnt and BMP signaling pathways stimulating follicle stem cell activity and promoting secondary hair growth and gene expression.
101 citations
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June 2003 in “The EMBO Journal” Phospholipase Cδ1 is crucial for normal skin and hair development.
5 citations
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October 2020 in “Frontiers in Cell and Developmental Biology” This study found that the trichogenicity of cultured human outer root sheath follicular keratinocytes decreased with longer cultivation periods and was significantly influenced by the expression of the transcription factor FOXA2.
August 2025 in “Biomolecules” This review explores the role of FGF signaling in hair follicle development and highlights its potential as a new therapeutic target for hair loss, which could surpass existing treatments in terms of efficacy and safety.
June 2013 in “The mental health clinician” This review discusses Dr. Atul Butte's lecture on transforming vast data sets into drug discovery insights and highlights the importance of merging clinical, molecular, and environmental data for personalized medicine, but it reports no new clinical results.
17 citations
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November 2021 in “Journal of Cosmetic Dermatology” This review discusses treatment options for androgenetic alopecia, highlighting the need for personalized, evidence-based approaches but reports no new clinical results.
8 citations
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October 2022 in “Regenerative Therapy” This review discusses regenerative medicine approaches for treating alopecia, including mesenchymal stem cell therapies and platelet-rich plasma, but reports no new clinical results, emphasizing the need for further study.
5 citations
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March 2022 in “Frontiers in Medicine” This review analyzed 17 recent clinical trials on platelet-rich plasma for androgenetic alopecia but reports no new clinical results; the authors seek a consensus on optimal PRP use.
5 citations
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September 2017 in “Plastic and Aesthetic Research” This study aimed to assess whether using minoxidil alongside nutritional cyclical supplements could boost hair regrowth without antiandrogens or enzyme blockers, focusing on hair root strengthening. Results are not reported.
In this study, incorporating cetirizine into transferosome formulations significantly enhanced hair growth in mice and boosted IGF-1 and VEGF levels, suggesting that this method could be a promising alternative to traditional hair growth treatments, though further studies are needed to confirm its safety and suitability.
February 2026 in “Biomedicines” This review highlights advancements in nanotechnology-based treatments for androgenetic alopecia, noting that these strategies could improve targeting and modulation of hair follicle environments compared to traditional therapies like minoxidil and finasteride, but also emphasizes challenges around safety, manufacturing, and regulation.
January 2026 in “Preprints.org” This review highlights recent advancements in nanotechnology-based approaches for treating androgenetic alopecia, focusing on enhancing drug delivery to hair follicles, controlled release, and follicular microenvironment modulation, while addressing safety, manufacturing, and regulatory challenges for clinical application.
July 2025 in “Journal of the Dermatology Nurses’ Association” This article reports on the 2025 Annual Dermatology Nurses’ Association Convention, emphasizing its role in education, networking, and advocacy advice, and provides insights into managing stress-related skin issues and hair loss, as well as dermatology treatment advances.
June 2025 in “Naunyn-Schmiedeberg s Archives of Pharmacology” This literature review reports that certain herbal remedies, such as rosemary, green tea, and ginseng, have shown promise in promoting hair growth and improving hair density, though variability and study design limitations highlight the need for more rigorous research.
March 2025 in “JEADV Clinical Practice” This article explores the role of ketoconazole shampoo in hair care beyond treating dandruff and seborrhoeic dermatitis, suggesting it may reduce hair shedding and chronic scalp inflammation, potentially complementing treatments for androgenetic alopecia.
July 2024 in “Pharmaceutics” In a mouse model of androgenetic alopecia, this study found that a novel hydrogel containing minoxidil-incorporated engineered exosomes (Gel@MNs) enhanced hair regeneration more effectively than conventional minoxidil, increasing hair follicle number and size while reducing skin irritation.
This case study reports that a 14-year-old female with loose anagen hair syndrome and trichotillomania initially improved with topical minoxidil and counseling, but relapsed after a year, highlighting treatment challenges.
In this case study, a patient with long-standing androgenic alopecia and lupus showed a satisfactory response to treatment with oral and topical minoxidil after suboptimal outcomes with previous treatments.
July 2026 in “JAAD reviews.” Female Pattern Hair Loss affects women's quality of life, with limited treatment options and a need for more research.
321 citations
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March 2015 in “Nature” This study found that super-enhancers are essential for hair follicle stem cell identity, lineage commitment, and plasticity in mice, with SOX9 being a key regulator of these chromatin dynamics.
34 citations
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August 2016 in “Scientific Reports” This study validated a protocol for inducing surface ectoderm differentiation from human induced pluripotent stem cells and highlighted the role of TGFβ signaling pathways in this process.
September 2021 in “Physiology News” This abstract contains only graphic design specifications and reports no new research findings.
December 2024 in “Journal of Investigative Dermatology” The conference highlighted new treatments and research in pediatric skin conditions, emphasizing collaboration and innovation.
This study identified ISX9 as a novel agonist of the Wnt/β‐catenin pathway, which promoted hair regrowth in mice and may offer a therapeutic approach for alopecia.