Nanotechnology-Based Strategies for Hair Regeneration: Mechanistic Insights and Translational Perspectives for Androgenetic Alopecia

The document explores the potential of nanotechnology-based strategies for treating androgenetic alopecia (AGA), a common form of hair loss. It highlights the limitations of traditional treatments like minoxidil and finasteride and suggests that nanotechnology can enhance drug delivery directly to hair follicles, improving efficacy and minimizing side effects. Various nanocarriers, such as polymeric nanoparticles and lipid-based carriers, are discussed for their ability to improve drug stability and penetration. The integration of nanotechnology with microneedle systems is noted as a promising approach for effective AGA treatment. However, challenges such as long-term safety and regulatory hurdles must be addressed for clinical application. Future research will focus on stimuli-responsive nanomaterials and personalized approaches to optimize outcomes.