Characterization of Growth Secondary Hair in Min Pig Activated by Follicle Stem Cell Stimulated by Wnt and BMP Signaling Pathway

This study explores the mechanisms of secondary hair growth in Min pigs, which is stimulated by follicle stem cells through the Wnt and BMP signaling pathways. The research involved 27 pigs (9 each from Min, Yorkshire, and Berkshire breeds) and found that Min pigs, unlike the other breeds, retain secondary hair growth into adulthood, aiding their adaptation to cold environments. The study highlights the significant role of the Wnt pathway over BMP in stimulating hair growth, with Min pigs showing distinct hair follicle structures and gene expressions. These findings provide insights into hair regeneration mechanisms, suggesting potential applications in human hair loss treatments.