Enrichment of Specific Hair Follicle-Associated Cell Populations in Plucked Hairs Offers an Opportunity to Study Gene Expression Underlying Hair Traits

    Rakan Naboulsi, J. Cieślak, Denis J. Headon … Gabriella Lindgren
    Studysummary This study compared RNA-seq results from horse plucked-hair and skin-biopsy samples, finding that plucked hairs were enriched with hair-follicle keratinocytes, while biopsies showed enrichment for other cell types.
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    Research cited in this study 8

    1. Assessing Protein Sequencing in Human Single Hair Shafts of Decreasing Lengths Forensic Science International Genetics · 2019
    2. Skin Cell Heterogeneity in Development, Wound Healing, and Cancer Trends in cell biology · 2018
    3. Human Hair Follicle Transcriptome Profiling: A Minimally Invasive Tool to Assess Molecular Adaptations Upon Low-Volume, High-Intensity Interval Training Physiological Reports · 2017
    4. Scratching the Surface of Skin Development Nature · 2007
    5. The Hair Cycle Journal of Cell Science · 2006
    6. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    7. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    8. Removal of Intact Hair Papilla and Connective Tissue Sheath by Plucking Anagen Hairs Journal of Investigative Dermatology · 1967

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