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research Analysis of Sequences Controlling Tissue-Specific and Hyperproliferation-Related Keratin 6 Gene Expression in Transgenic Mice

26 citations , February 1998 in “DNA and Cell Biology”

This research identified that the constitutive and inducible expression of the Keratin 6 gene in transgenic mice skin is controlled by multiple regulatory elements spread throughout its 5' flanking region.

research Ovine KRTAP36-2: A New Keratin-Associated Protein Gene Related to Variation in Wool Yield

November 2023 in “Genes”

This study identified a new gene in sheep, KRTAP36-2, discovering variants associated with wool yield. Variations in this gene were linked to the efficiency of fleece conversion from greasy to clean, which may enhance wool production.

research A 5'-upstream region of a bovine keratin 6 gene confers tissue-specific expression and hyperproliferation-related induction in transgenic mice.

46 citations , May 1995 in “Proceedings of the National Academy of Sciences”

This study demonstrated that a specific 9-kbp fragment of the bovine keratin 6 gene effectively directs tissue-specific and inducible expression in transgenic mice, suggesting potential applications for targeted gene therapy in hyperproliferative skin conditions.

research Expression of hair-related keratins in a soft epithelium: Subpopulations of human and mouse dorsal tongue keratinocytes express keratin markers for hair-, skin- and esophageal-types of differentiation

128 citations , March 1989 in “Experimental Cell Research”

Hoxc13 is important for hair and tongue development by controlling hair keratin genes.

research Molecular Evolution of The Keratin‐associated Protein Gene Family

September 2009 in “Encyclopedia of Life Sciences”

This paper discusses the role of the KRTAP gene family in the evolution of mammalian hair and its potential link to hair-related disorders, but reports no new research findings.

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Community Join

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community Keratin microspheres - breakthrough

14 upvotes 2 years ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community Mature hairlines in general and defining them

13 upvotes 5 years ago

A "mature hairline" is subjective and may not indicate future stability. Finasteride and minoxidil are suggested treatments for hair loss.

community Finasteride stopped working. Losing ground on Dutasteride.

in Finasteride/Dutasteride 17 upvotes 4 months ago

The user started with Finasteride at 19, added Dutasteride and Minoxidil at 26, but continues to experience hair loss. Suggestions include checking health markers, considering genetics, and possibly increasing Minoxidil dosage.

community How much difference hair fibers and mousse make

in Styling 1459 upvotes 1 year ago

The user applies Rogaine foam, Toppik hair fibers, and Tresemme mousse to improve hair appearance and has restarted finasteride after a year off. They are considering a hair transplant and are working on self-esteem related to hair loss.

community 23-Year-Old Trans Male: Concerns About Minox and Finasteride for Hair Loss

in General 298 upvotes 1 year ago

A 23-year-old trans male is concerned about hair loss and is considering treatments like topical and oral minoxidil and finasteride. They are worried about the effects on their pet and hormone balance and are seeking affordable options within their existing medical team.

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learn Overview

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