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This review discusses current topical treatments, natural products, and complementary therapies for androgenetic alopecia, but it reports no new clinical results.

This study found that peimine treatment significantly improved wound healing and tissue regeneration in mice by enhancing wound closure, granulation tissue formation, and epidermal thickness, with effects linked to activation of the Notch1 signaling pathway.

In this study, the researchers report that a modified epimorphin-derived peptide shows potential for hair follicle regeneration, especially when used with 1% minoxidil in mice.

This study observed that liposomes encapsulating minoxidil and PEP penetrate the skin at a slower rate but may reach deeper layers compared to a foam formulation.

This review discusses the historical development, mechanisms of action, and potential new clinical applications of the drug cepharanthine, highlighting its multi-faceted pharmacological properties; it reports no new clinical results.

This study found that using elastic nano-liposomes to deliver palmitoylethanolamide improved its transdermal delivery and enhanced its skincare effects, with minimal cytotoxicity and no allergic reactions observed.

This study found that P. cornucopiae extract showed antioxidant and protective effects on human skin fibroblasts, suggesting its potential as an antiaging agent by preventing oxidative stress-induced collagen breakdown.

This study found that the natural alkaloid cepharanthine effectively inhibited porcine epidemic diarrhea virus infection in newborn piglets.

This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.

In this study, the researchers developed a novasome vesicle carrying bovine placenta extract, which demonstrated superior hair growth effects in rats compared to traditional minoxidil and PE-loaded liposomes, and showed good stability and physical characteristics over 90 days at 4°C.

This study found that cepharanthine can inhibit gastric cancer cell activity by inducing oxidative stress and altering energy metabolism, suggesting its potential for gastric cancer treatment.

In this study, gold nanoparticles-embedded ceria nanoparticles with enhanced antioxidant activities effectively reduced inflammation and colon injury in a colitis mouse model, suggesting their potential as a nano-therapeutic for inflammatory bowel disease.

This study found that cephalanthine inhibited the growth of gastric cancer cells in vitro and in vivo by inducing oxidative stress and altering energy metabolism, suggesting its potential as a treatment for gastric cancer.

This study introduced hydrogel microneedles loaded with palladium nanoparticles, which utilize the inherent cytotoxicity of polyethyleneimine to enhance the effectiveness of doxorubicin in treating melanoma, achieving a tumor inhibition rate of up to 98% in a murine model.

This special issue contains abstracts from the ASA 40th Annual Meeting, providing an overview of various studies without reporting new primary results.

This study found that the addition of SPACE peptide significantly enhanced the penetration of amniotic membrane stem cell metabolites in mice, with only very mild irritation observed.

In this study, 3% peppermint oil promoted hair regrowth faster than 3% minoxidil in mice and showed strong antibacterial activity against P. ovale.

This study found that dissolving microneedles loaded with platinum nanozymes induced faster hair growth in an androgenetic alopecia model than daily minoxidil applications, with no significant safety concerns.

This study found that goat placenta extract, when combined with PEGylated liposomes and microspicule gel, significantly promoted hair regrowth in patients experiencing hair loss due to chemotherapy by enhancing hair cell proliferation without causing skin irritation over a 12-week application period.

In this study, PEVIII, a nanocomposite chitosan-coated vesicle containing both α-hederin and hederacoside C, demonstrated notable antibacterial activity against Pseudomonas aeruginosa in a keratitis model, showing significant lesion reduction, tissue improvement, and decreased bacterial load and inflammatory markers compared to other treatments.

Peppermint oil promotes hair growth and fights bacteria better than minoxidil.

This study found no significant difference in anagen rate improvement between the CYP-based dietary supplement and placebo in women over 60 with telogen effluvium, possibly due to variable patient inclusion related to hair growth seasonality.

This study found that the PVP protocol, combining Peptichemio, vincristine, and 6-methylprednisolone, resulted in remission for diffuse non-Hodgkin's lymphomas with moderate side effects.

This study developed a peptide-based topical delivery system that enhanced hair growth with reduced systemic exposure to finasteride, showing efficacy comparable to 5% minoxidil in vivo while using significantly less finasteride than oral doses.

This review reports that the compound Cepharanthine shows promise as a cancer therapy by inducing cell death, arresting cell growth, inhibiting tumor progression, modulating key oncogenic pathways, and reversing multidrug resistance, suggesting its potential for further investigation in oncology.

This study found that the penetration enhancer SEPA™ significantly increased both the speed and amount of hair growth from minoxidil in balding stumptail macaques compared to Rogaine®.

This review highlights cepharanthine as a promising candidate for COVID-19 treatment due to its antiviral activity against SARS-CoV-2 and favorable pharmacokinetic and safety profile, but reports no new clinical results.

In this study, Epimedii Folium extract was found to enhance melanin production and promote pigmentation through mechanisms involving the MAPK/ERK1/2 pathway in both in vitro and in vivo models.

This article reviews the development and challenges of skin penetration enhancers, highlighting their limitations in compatibility and safety, and reports no new clinical findings.