1 citations
,
December 2014 in “Scanning” This study used multiphoton microscopy to successfully visualize rabbit skin microstructure, highlighting its noninvasive potential for future skin research related to diseases and wound healing.
January 2024 in “IFMBE proceedings” 166 citations
,
February 2020 in “Advanced Functional Materials” This study reports that a novel programmable device delivering VEGF through miniaturized needles significantly improved healing outcomes in diabetic mice's chronic wounds compared to traditional topical treatments.
This article discusses a novel device for applying mediums to human and animal tissues and reports no new clinical results, focusing on its potential for precise applications and enhanced cell transplants.
8 citations
,
March 2023 in “BMC Research Notes” This pilot study explored a new method using laser-capture microdissection and 16S rRNA gene sequencing to analyze the human scalp hair follicle microbiome more accurately, revealing region-specific variations in microbial diversity and abundance.
January 2002 in “Europe PMC (PubMed Central)” This study presents a follicular automaton model that simulates human hair cycle dynamics and can reproduce hair patterns similar to diffuse or androgenetic alopecia by incorporating spatially heterogeneous parameters and follicle miniaturization.
This article discusses disruptions in hair cycle dynamics and follicular miniaturization associated with patterned hair loss, emphasizing androgen-related changes, and reports no clinical findings.
16 citations
,
November 2020 in “In Vitro Cellular & Developmental Biology - Animal” This study explored the use of "microfollicles," a human hair follicle organoid model, as an in vitro tool for testing hair-growth substances, finding up to 75% overlap in gene expression changes with human clinical biopsy responses to minoxidil, indicating its potential for pre-clinical substance testing.
3 citations
,
April 2021 in “Journal of Cosmetic Dermatology” In this study, the researchers found that a manual micrometer caliper is a reliable tool for planning hair transplant surgery and accurately measures the short axis of the hair shaft.
8 citations
,
April 1999 in “Dermatologic Clinics” This study evaluates if using a dissecting stereomicroscope affects the rate of hair follicle transection during graft dissection, but reports no new conclusive results.
February 2015 in “Dermatologic Surgery” This article discusses various affiliations of the authors with no reference to new research findings.
3 citations
,
October 2019 in “Pharmaceutics” This study suggests that newly developed micro-pigment-encapsulated biodegradable microneedles accurately implant pigments in pig cadaver skin, potentially advancing scalp micro-pigmentation methods.
5 citations
,
August 2021 in “STAR Protocols” This article outlines a protocol for scanning electron microscopy of murine skin and primary keratinocyte monolayers, providing a guide for sample preparation and examination.
24 citations
,
March 2024 in “Small Science” This review discusses the potential applications and advantages of encapsulating single cells for use in therapeutics and diagnostics, while also evaluating various methods for effectively creating and sorting single-cell units despite challenges in production and cost.
96 citations
,
April 2017 in “Oncotarget” This study found that nanoemulsions of different sizes vary in their ability to penetrate skin layers, with smaller sizes aiding transdermal delivery and potential applications in transcutaneous immunization.
1 citations
,
August 2002 in “Zeitschrift für Hautkrankheiten” Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.
25 citations
,
March 2002 in “Scanning” This study highlights confocal microscopy as a promising, minimally invasive tool for assessing hair morphology and internal structures, making it valuable for cosmetic hair assessments.
November 2024 in “Journal of Investigative Dermatology” The research aims to better understand hair follicle regulation and find new treatments for hair loss.
April 2019 in “Lincoln (University of Nebraska)” This study engineered a programmable platform using miniaturized needle arrays for drug delivery, showing improved wound healing outcomes in diabetic mice compared to standard topical treatments.
5 citations
,
January 2019 in “Methods in molecular biology” In this study, researchers showed that multiphoton microscopy with fluorescent protein tagging enables single-cell imaging and tracking in live transgenic mice, offering new insights into cell dynamics in stem cell research compared to traditional histological methods.
June 2012 in “International journal of scientific research” In this study, Raman micro-spectroscopy did not support the hypothesis of structural changes in hair follicles due to miniaturization in women with androgenetic alopecia.
8 citations
,
June 2019 in “Scientific Reports” This study found that the retinoid receptor and PPAR pathway are involved in hair follicle miniaturization in androgenetic alopecia, alongside androgen receptors.
January 2025 in “Journal of Pharmaceutical Research Science & Technology” This review explores the potential, challenges, and recent advancements of dissolving microneedles in drug delivery, summarizing their varied applications and current limitations without providing new clinical results.
2 citations
,
December 2024 in “International Journal of Pharmaceutics” In animal studies, this research found that minoxidil-loaded air-pocket microneedles improved hair loss treatment efficiency compared to topical application, while effectively sealing punctured skin openings.
January 2013 in “프로그램북(구 초록집)” This study found that using a 0.5mm roller for microneedle therapy increased hair growth in mice and significantly affected the expression of hair growth-related molecules like VEGF.
1 citations
,
July 1998 in “Hair transplant forum international” This commentary discusses the use of microscopes in hair restoration surgery but provides no specific results or new insights.
4 citations
,
December 2020 in “Journal of Dermatology” This study suggests that impaired autophagy may be a potential mechanism contributing to androgenetic alopecia, as observed in miniaturized hair follicles from balding scalps.
11 citations
,
July 2023 in “Applied Nanoscience” February 2026 in “Journal of drug targeting” This study found that combining laser ablation with nanoparticulate drug formulations effectively enhanced the skin and follicular delivery of hydrophilic drugs like minoxidil and minocycline in preclinical models.
2 citations
,
May 2025 in “Advanced Science” In this study, researchers developed a method to create skin organoids using spinning bioreactors, facilitating efficient high-throughput drug screening, and found that Minoxidil activates the Wnt/beta-catenin signaling pathway in these models.