Hair Loss Physiology and Transplantation Principles

    January 2020
    Tymon Tai, Michael Chow, Amit Kochhar
    TLDR Hair loss is caused by hormonal changes that shorten hair growth phases and shrink hair follicles.
    The document discussed the physiological mechanisms behind hair loss, particularly focusing on male and female patterned hair loss. It highlighted two main disruptions: hair cycle perturbation and follicular miniaturization. Androgens were noted to alter the hair cycle by shortening the anagen phase, leading to shorter hair that may not reach the skin's surface. Additionally, during the catagen/telogen phase, follicles miniaturized, transforming thick terminal hairs into thin vellus hairs, decreasing the terminal to vellus hair ratio and contributing to balding. The document also touched on principles of hair transplantation, although specific transplantation techniques or outcomes were not detailed in the provided text.
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