December 2025 in “International Journal of Dermatology” This systematic review reported that while combining low-dose oral minoxidil with Janus kinase inhibitors may enhance treatment outcomes in alopecia areata, the evidence remains weak due to limited sample sizes and potential publication bias, and more rigorous trials are necessary to assess efficacy and safety.
January 2023 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” This source explores treatments for male-pattern baldness, highlighting finasteride, which reduces DHT levels to support hair growth, and minoxidil, used for vasodilation and hair health, though the exact mechanisms remain partly unclear.
13 citations
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January 2021 in “The American journal of gastroenterology” In this study, sirolimus treatment reduced the size of venous malformations and improved anemia, transfusion dependence, and quality of life in patients with blue rubber bleb nevus syndrome, though mild adverse effects were reported.
1 citations
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March 2009 in “The Journal of Urology” This review discusses trials on therapies for benign prostatic hyperplasia and reports that combination treatment is more effective than monotherapy for symptom relief and slowing disease progression in men with moderate to severe symptoms and enlarged prostate glands.
44 citations
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October 2017 in “Scientific Reports” This study found that far-infrared radiation preconditioning significantly enhanced the proliferation, survival, and migration of bone marrow-derived stem cells in vitro, indicating potential therapeutic benefits for cardiac ischemia treatment.
28 citations
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September 2019 in “International Journal of Nanomedicine” This study found that minoxidil nanoparticles increased drug delivery to hair follicles and improved hair growth more effectively in mice than conventional minoxidil formulations.
104 citations
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March 1987 in “Journal of The American Academy of Dermatology” Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.
6 citations
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April 2022 in “Biomedicine & pharmacotherapy” This review discusses the potential of using triads of repositioned medicines targeting multiple pathogenic mechanisms to prevent or delay retina degeneration, but reports no new results.
February 2024 in “Practical Diabetes” This study showed that spironolactone effectively reduces morbidity and mortality in moderate to severe heart failure with reduced ejection fraction, but its benefits in heart failure with preserved ejection fraction are less clear.
51 citations
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April 1982 in “Lancet” This study found that multiple treatment regimens for refractory hypertension were effective in controlling blood pressure in most patients, with diazoxide being the most effective but least tolerable option.
1 citations
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August 2018 in “Journal of The American Academy of Dermatology” Combination of minoxidil and finasteride is more effective in increasing hair diameter than minoxidil alone for female-pattern hair loss.
July 1987 in “Reactions (Auckland)” Oral minoxidil may slow male pattern baldness and cause body hair growth, but hair loss can happen after stopping it.
2 citations
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December 2024 in “International Journal of Pharmaceutics” In animal studies, this research found that minoxidil-loaded air-pocket microneedles improved hair loss treatment efficiency compared to topical application, while effectively sealing punctured skin openings.
13 citations
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November 2014 in “Pediatric emergency care” This study reports that the ingestion of a small amount of topical minoxidil by a child resulted in significant intoxication, suggesting the need for enhanced child-resistant packaging.
January 2020 in “Medical Journal of Clinical Trials & Case Studies” This study found that topical minoxidil can be effective in preventing flap necrosis during latissimus dorsi flap reconstruction in patients who have undergone neoadjuvant chemoradiation.
October 2023 in “European journal of dermatology/EJD. European journal of dermatology” In this study, I-PRF, a blood-derived biomaterial without anticoagulants, was found to inhibit melanin production and reduce oxidative stress damage in a rat model of melasma, suggesting it as a safe and cost-effective treatment option.
September 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil may be a promising alternative to topical minoxidil for hair loss.
January 2022 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” This review discusses the efficacy and molecular pharmacology of topical minoxidil for hair loss and highlights innovations in delivery systems but reports no new clinical results.
August 2026 in “Pharmaceutics” In this study, radiofrequency microporation significantly improved topical minoxidil delivery and hair regrowth in a mouse model of androgenetic alopecia, with minimal systemic exposure compared to oral administration, suggesting it could be a promising needle-free option for topical therapy.
28 citations
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May 1994 in “The Journal of Urology” This study found that topical application of 2% minoxidil solution was not effective in improving erectile dysfunction in the majority of participants.
January 2024 in “Tropical Journal of Pharmaceutical Research” This study found that 5% minoxidil liniment was more effective than 2% minoxidil for treating female pattern hair loss over 6 months, with the higher dose showing significant improvement, especially in severe cases.
January 2025 in “International Journal of Dermatology” This letter to the editor discusses blood pressure changes in patients taking low-dose oral minoxidil but reports no new research findings.
7 citations
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June 2021 in “Cureus” This case report discusses minoxidil-induced anasarca as a potential side effect in patients using minoxidil for hypertension, emphasizing the importance of recognizing it for early diagnosis and management.
1 citations
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May 2013 in “Polymer-korea” This study found that using dissolving micro-needles with minoxidil promoted more hair growth in an animal model compared to minoxidil treatment alone or no treatment.
1 citations
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September 2023 in “Journal of The American Academy of Dermatology” This abstract reviews the use of low dose oral minoxidil as a monotherapy for hair loss and reports no new clinical data.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Combining minoxidil with microneedling leads to better hair regrowth than using minoxidil alone.
22 citations
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January 1999 in “Journal of Toxicology Clinical Toxicology” This report describes the first documented case of an oral overdose of the extra strength 5% minoxidil solution, resulting in severe hypotension and requiring intensive medical intervention.
28 citations
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April 2008 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry” This study identified a weak interaction between minoxidil and ß-cyclodextrin in solution, forming an inclusion complex with a 1:1 molar ratio.
27 citations
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January 1986 in “PubMed” This study found no significant difference in hair growth between patients with extensive alopecia areata treated with 1% minoxidil and those given a placebo.
46 citations
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June 1990 in “Archives of dermatology” In this study, combination therapy with 5% minoxidil and 0.5% anthralin showed some cosmetic improvement in 11% of patients with severe treatment-resistant alopecia areata, with hair regrowth starting by week 12.