49 citations
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October 1994 in “Annals of Oncology” Minoxidil not effective in preventing chemotherapy-induced hair loss.
January 2023 in “Journal of The American Society of Nephrology” This article discusses the potential benefits and challenges of metatrials as a new clinical trial methodology during COVID-19 and reflects on its application in nephrology, but reports no new results.
July 2022 in “Journal of Investigative Dermatology” This study found that a new alcohol-free minoxidil hydrogel formulation showed comparable in vitro efficacy and skin absorption to the commercial minoxidil product for treating androgenetic alopecia.
6 citations
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October 2011 in “Archives de pédiatrie” This case report describes a young girl who experienced vasoplegic shock and prolonged tachycardia after ingesting hair lotion containing minoxidil, highlighting the need for extended monitoring due to potential persistent hemodynamic issues.
April 2025 in “Archives of Dermatological Research” The combination of finasteride and minoxidil is as safe and effective as minoxidil alone for improving hair growth in men.
12 citations
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February 1999 in “British Journal of Dermatology” In this study, topical minoxidil was reported to increase fenestration in follicular capillary walls around anagen hair bulbs in male rats.
4 citations
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January 2009 in “International journal of trichology” Minoxidil topical foam is a better, less irritating treatment for hair loss.
August 2023 in “Drug Design Development and Therapy” This study found that minoxidil may treat androgenetic alopecia by affecting hormonal and enzymatic pathways, identifying new targets CYP17A1 and CYP19A1 and demonstrating its inhibition of androgenic receptors.
April 2026 in “microPublication” In this study, researchers explored whether minoxidil, a common treatment for androgenetic alopecia, may have estrogenic activity and found preliminary evidence suggesting it could act as a partial agonist of Estrogen Receptor α (ERα).
March 2005 in “Journal of The American Academy of Dermatology” The two lotions used day and night may be a good alternative to minoxidil for hair loss treatment with better cosmetic effects and tolerance.
September 2024 in “Journal of the American Academy of Dermatology” In this pilot study, minoxidil-treated scalp skin grafts from hair loss patients on mice showed increased expression of key anti-aging biomarkers and hair regrowth, suggesting minoxidil as a potential anti-aging agent by boosting VEGF-A production in hair follicles.
17 citations
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March 1985 in “Journal of The American Academy of Dermatology” Minoxidil can lower blood pressure in some people.
95 citations
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December 1980 in “The New England Journal of Medicine” Minoxidil helped bald patient regrow hair.
1 citations
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April 2025 in “Drug Delivery and Translational Research”
March 2005 in “Inpharma Weekly” China approved Sinovac's flu vaccine, Japan approved RiUP for female hair loss, and Nippon Kayaku's three cancer drugs.
192 citations
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March 1998 in “British Journal of Dermatology” This study found that minoxidil significantly increases VEGF mRNA and protein expression in dermal papilla cells, suggesting a role in enhancing hair follicle vascularization in androgenetic alopecia.
September 2026 in “Advanced Materials Technologies” In a mouse model study, researchers developed a methacrylated hyaluronic acid-based hydrogel microneedle patch co-loaded with finasteride and a carbon monoxide-releasing molecule for androgenetic alopecia, which showed better hair regrowth and safety compared to traditional treatments, offering an innovative approach with minimized systemic side effects.
8 citations
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October 2015 in “PubMed” Recent Phase III trials reported that once daily 5% minoxidil foam significantly increased hair count in women with female pattern hair loss and was shown to be as effective as twice daily 2% minoxidil solution.
Ivarmacitinib effectively regrows hair in severe alopecia areata.
January 2008 in “Abstracts” Minoxidil sulfate gel can be used to treat hair loss.
October 2019 in “International Journal of Research in Dermatology” This study found that combining topical minoxidil with oral spironolactone improved hair loss outcomes in women with female pattern hair loss when compared to minoxidil alone, but benefits plateaued after 6 months.
March 1991 in “International Society of Hair Restoration Surgery”
14 citations
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January 2020 in “International Journal of Biological Sciences” This study found that ranitidine and finasteride may have cardiovascular and renal protective effects in mice by inhibiting TMAO synthesis and improving gut microbiota composition.
This study reviewed contemporary literature and found that combining minoxidil with topical finasteride, biologic adjuvants, or delivery innovations might enhance treatment effectiveness for androgenetic alopecia compared to minoxidil alone, although diverse outcomes and incomplete data limit broader conclusions.
January 2026 in “SSRN Electronic Journal” 9 citations
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July 2022 in “British Journal of Pharmacology” In this study, topical MR blockade improved delayed wound healing in glucocorticoid-pretreated mice by promoting anti-inflammatory macrophages and enhancing angiogenesis.
August 2024 in “PLoS ONE” This study reviewed randomized controlled trials to assess whether adding platelet-rich plasma injections to a Minoxidil regimen offers any benefit in treating androgenetic alopecia, but results are not reported in the abstract.
1 citations
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January 2019 in “Advances in Medical Sciences” This study found that a combination of azelaic acid, minoxidil, and caffeine significantly reduced skin flap necrosis in rats, likely by increasing nitric oxide content and iNOS expression, compared to individual treatments.
This paper suggests that topical minoxidil might help treat male-pattern alopecia and alopecia areata, but its effectiveness depends on patient selection and formulation, with side effects primarily being skin reactions.
1 citations
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April 2018 in “Медицинский совет” In this review, the authors report that topical minoxidil effectively stimulates hair growth in androgenic alopecia and to a lesser extent in nasal alopecia, particularly in early stages, with minimal and typically short-lived adverse skin reactions, but no systemic side effects.