27 citations
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April 1992 in “Biochemical Journal” Minoxidil reduces lysine hydroxylase in skin cells.
5 citations
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December 2022 in “Annals Academy of Medicine Singapore” This review reports that nirmatrelvir-ritonavir has significant drug-drug interactions with many common dermatological medications, whereas molnupiravir may be an alternative therapy due to the absence of such interactions observed so far.
September 2025 in “International Journal of Trichology” This study discusses the use of low-dose oral minoxidil for hair loss, noting that while it is popular and considered safe, it can mimic Cantú syndrome effects such as hypertrichosis and pericardial effusion, necessitating careful monitoring and caution during prescription.
February 2024 in “Current Medicinal Chemistry” In this study, minoxidil nanoparticles significantly increased hair growth rate in C57BL/6 mice compared to traditional minoxidil, suggesting enhanced effectiveness and potential as a new formulation.
August 2026 in “International Journal of Dermatology” This article discusses the availability of data from TriNetX for research purposes and reports no new findings.
August 2026 in “LUMEN ET VIRTUS” In this study, low-dose oral minoxidil for androgenetic alopecia was generally safe, showing small average changes in blood pressure and heart rate with infrequent cardiovascular issues, though monitoring is essential, especially in patients with conditions like hypertension or arrhythmias.
November 2023 in “PubMed” This study found that treating mice with naringenin, alone or combined with minoxidil, significantly increased hair growth and follicle diameter and quantity, likely due to its antioxidant and anti-inflammatory properties.
July 2021 in “Journal of reports in pharmaceutical sciences” This study evaluated a new aqueous-based nanosuspension of minoxidil for treating androgenetic alopecia and reported it was as effective as the commercial product but had better safety and tolerability, potentially improving patient compliance.
1 citations
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December 2022 in “Indian pediatrics/Indian Pediatrics” A toddler who accidentally swallowed hair growth medicine experienced serious heart-related side effects but recovered after hospital treatment.
October 2025 in “International Journal of Advanced Research in Science Communication and Technology” This source reviews recent data on topical minoxidil, evaluating its pharmacology, mechanism of action, clinical effectiveness, and side effects in treating hair loss, although its precise mode of action remains unclear.
June 2023 in “Journal of Cosmetic Dermatology” This research highlights that while minoxidil and 5-alpha reductase inhibitors are commonly used for treating pattern hair loss, there is limited evidence supporting their relative effectiveness in women compared to men.
February 2023 in “Seven Editora eBooks” This study aims to compare the differences in adverse reactions and efficacy between topical and oral use of minoxidil for hair growth, with a focus on newer, lower-dose oral applications originally used for hypertension.
1 citations
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January 2013 in “PubMed” In this study, topical adenosine 0.75% and minoxidil 5% had similar recovery rates for androgenetic alopecia, but patients reported higher satisfaction with adenosine due to quicker hair loss prevention and new hair appearance.
May 2024 in “International journal of medicine and psychology.” This article describes an increase in the detection of heart failure among young people and discusses the development of the drug Uperio for its treatment and support.
42 citations
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August 2012 in “Psychoneuroendocrinology” Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.
137 citations
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May 1984 in “Journal of Investigative Dermatology” Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.
June 2025 in “Journal of Population Therapeutics and Clinical Pharmacology” This study found that the combination of minoxidil, microneedling, and platelet-rich plasma was more effective for androgenetic alopecia than minoxidil alone, although adverse effects were noted.
6 citations
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August 2024 in “Biomacromolecules” This study introduces a novel in vitro model for clubfoot fibrosis to enable high-throughput drug screening and found that while the model increased collagen deposition, the antifibrotic drug minoxidil effectively inhibited the expression of collagen cross-linking enzymes.
October 2015 in “Elsevier eBooks” Minoxidil is effective for hair growth and safe for long-term use.
1 citations
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November 2023 in “SKIN The Journal of Cutaneous Medicine”
397 citations
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February 2004 in “British Journal of Dermatology” This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.
August 2025 in “Archives of Dermatological Research” This systematic review and meta-analysis suggest that oral minoxidil may be a safer and more effective option for children with hair disorders and refractory hypertension, though further large-scale trials are needed.
5 citations
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January 2015 in “Journal of clinical & experimental dermatology research” This study found that the MorrF topical solution combination showed significantly better hair growth improvements than Minoxidil alone in male patients with Androgenetic Alopecia.
23 citations
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January 2011 in “International Journal of Immunopathology and Pharmacology” In this small study, topical minoxidil 2% was associated with an increase in normal hair shaft production in patients with Monilethrix without any reported side effects.
3 citations
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January 1988 Minoxidil helps hair grow, especially in people with mild hair loss.
7 citations
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April 2025 in “Science Advances” This study suggests that a biomaterial-based approach using microneedles and ion solutions to deliver SiO3 2− ions may disrupt inflammatory cycles and improve outcomes in inflammatory dilated cardiomyopathy (iDCM).
1 citations
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January 2020 in “Surgical & Cosmetic Dermatology” This article examines the potential of using oral minoxidil as an adjuvant treatment for patients with severe alopecia areata who do not respond to increased doses of Janus kinase inhibitors, but provides no new clinical results.
8 citations
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October 2016 in “Journal of Investigative Dermatology” This study found that using mineralocorticoid receptor antagonists with glucocorticoid therapy improved wound healing in diabetic animals by enhancing keratinocyte proliferation and epithelialization.
This case report suggests that Minoxidil may be a potential cause of central serous chorioretinopathy in a 39-year-old cardiologist using it for androgenic alopecia.
3 citations
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May 1994 in “Journal of Pharmacology and Experimental Therapeutics” This study found that minoxidil sulfate stimulates Cl channels, potentially depolarization-activated and outwardly rectifying, in eccrine clear cells, while minoxidil itself stimulates Ca-insensitive K currents.